The influence of cognitive coping style and serotonin transporter gene polymorphism on neural correlates of emotion perception

这项成像遗传学研究使用功能磁共振成像(FMRI)和基于体素的形态测量(VBM)来检查认知应对方式。本研究的目的是：(1)认知应对方式对情绪面孔感知过程中神经激活的影响。(2)认知应对方式与皮质边缘系统的连通性。(3)认知应对方式对脑形态的影响。(4)5-羟色胺转运体基因多态性及其对神经激活、连通性和脑形态的调节。本研究将在美国贝塞斯达国家精神卫生研究所临床脑疾病分部(主任：Daniel R.Weinberger博士)进行。

This imaging genetics study examines cognitive coping style using functional Magnetic Resonance Imaging (fMRI) and Voxel-based Morphometry (VBM). The aims to be investigated are: (1) The influence of cognitive coping style on neural activation during the perception of emotional faces.(2) Cognitive coping style and connectivity in the corticolimbic system.(3) Influences of cognitive coping style on brain morphology.(4) The investigation of serotonin transporter gene polymorphisms and their modulation of neural activation, connectivity and brain morphology.This study will be performed at the Clinical Brain Disorders Branch (Director: Dr. Daniel R. Weinberger) at the National Institute of Mental Health, Bethesda, USA.