Dioxygen Activation by Nickel Complexes

特拉华州大学化学系的教员Charles Riordan教授得到了无机、生物无机和有机化学项目的支持，以制备活化分子氧的镍络合物。配体框架设计计划和复杂的物理技术是发展这种均匀的Ni（I）化学的两个支柱。 单价镍试剂的氧活化机制将探讨与动力学研究和通过检查氧化反应的范围提供活性镍氧物种与选定substrate.Oxidations采用分子氧是有吸引力的，作为一个环境负责的化学过程，在转换有机底物其氧化衍生物。 金属酶为使用第一行过渡金属催化氧化反应提供了灵感，合成和表征这些活性中间体所需的化学广度为本科生和研究生提供了丰富的培训环境。

Professor Charles Riordan, a faculty member in the Department of Chemistry at the University of Delaware, is supported by the Inorganic, Bioinorganic and Organometallic Chemistry Program to prepare nickel complexes that activate dioxygen. Ligand framework design plans and sophisticated physical techniques are two pillars for developing this homogeneous Ni(I) chemistry. The mechanism of oxygen activation by monovalent nickel reagents will be probed with kinetic studies and by examining the scope of oxidative reactions available to reactive nickel oxygen species with selected substrates.Oxidations employing dioxygen are attractive as an environmentally responsible chemical process in converting organic substrates to their oxidized derivatives. Metalloenzymes provide inspiration for using first row transition metals to catalyze oxidation reactions, and the breadth of chemistry required to synthesize and characterize these reactive intermediates provides a rich training environment of undergraduate and graduate students.