SGER: A New Approach to Assessing Microbial Risk in Drinking Water

0439389 Chu拟议的研究开发和检查一种新的分子技术的效率，用于鉴定和定量的水传播病原体。 提出了一种新的观点，毒力基因作为病原物种的生物标志物，可以使有效的分子定量的水样中的病原体。 如果成功，这项研究可以开发一种方法，将分子技术作为常规饮用水监测工具，并能够生成评估潜在健康威胁所需的定量数据。 预计还将开发一种新形式的剂量-反应关系，表示为毒力基因拷贝数与健康风险。

0439389ChuThe proposed research develops and examines the efficiency of a novel molecular technique for identification and quantification of waterborne pathogens. A novel view of virulence genes as biomarkers for pathogenic species is proposed and could enable effective molecular quantification of pathogens in water samples. If successful, this study could develop an approach for applying molecular techniques as routine drinking water monitoring tools, and enabling the generation of quantitative data, that is necessary for assessing potential health threats. It is also expected that a new form of dose-response relationship, expressed as copies of virulence genes vs. health risk, will be developed.