CAREER: A Bioanalytical System for Gene Expression Analysis on a Single Cell Basis

这项建议的目标是开发一个平台，在微流控环境中使用新型量子点FRET探针来评估mRNA的表达。对分子探针和微流控系统进行了表征，并使用基因表达模型对集成系统进行了演示。教育目标包括生物微电子机械系统课程开发，介绍一系列关于生物/纳米主题的研讨会，本科生指导和一个侧重于让高中生参与的外展部分。

0546012WangThe objective of this proposal is to develop a platform to assess mRNA expression using a novel quantum dot FRET probe within a microfluidic environment. Characterization of the molecular probe and the microfluidic systems are proposed followed by a demonstration of the integrated system using a gene expression model. The education goals include BioMEMS course development, introducing a seminar series on Bio/Nano topics, undergraduate mentoring and an outreach component focused on involving high school students.