CAREER: Ultra Low Power Passive Microsystems for Medication Compliance Monitoring

职业：用于药物依从性监测的超低功耗无源微系统pi: Rizwan BashirullahProposal No: ecs -0547057摘要该职业提案的重点是用于体内深层通信的超低功耗硅基无源微系统的开发。体内通信无源设备概念的核心是使用新型功率调节电路从弱入射场中清除射频能量，并使用高效电路拓扑从体内深处辐射到外部可检测的功率量。学术价值:本研究将：(1)对电压倍增器进行表征，以确定射频清除的输入电压、泄漏、可靠性和效率方面的基本权衡；(2)开发片上多谐振无源结构，从而实现放大器的集成和隔离；(3)评估和理解放大器和乘法器的相互作用；(4)使用人体生物幻影（即具有与人体等效电性能的解决方案）测试这些功率调节电路对体内信号的有效性。PI将以之前在植入式集成电子方面的研究为基础，并使用先进的CMOS技术，为体内通信的微型无源设备带来知识和创新的基本进步。更广泛的影响：集成射频子系统的微型无源器件的一个特定的高影响工程应用是药物依从性监测，据估计，美国医疗保健系统每年因不遵守药物治疗方案而造成的成本超过1000亿美元。该计划旨在促进对多学科研究的兴趣，为研究生、本科生和高中生提供创新集成电路技术的机会。拟议的教育计划将通过在综合研究和学术课程中包含理论和实验部分的教育模块，强调高中阶段代表性不足群体的参与。

CAREER: Ultra Low Power Passive Microsystems for Medication Compliance MonitoringPI: Rizwan BashirullahProposal No: ECS-0547057AbstractThis Career proposal focuses on the development of ultra low power silicon based passive microsystems for deep in-body communications. Central to the concept of in-body communication passive devices is the idea of RF energy scavenging from weak incident fields using novel power conditioning circuits and reradiating, from deep inside the body, externally detectable amounts of power using highly efficient circuit topologies.Intellectual Merit: This study will, (1) characterize voltage multipliers to determine fundamental tradeoffs in input voltage, leakage, reliability and efficiency for RF scavenging, (2) develop on-chip multi-resonant passive structures that will lead to amplifier integration and isolation, (3) evaluate and understand amplifier and multiplier interactions and (4) test the effectiveness of these power conditioning circuits for in-body signaling using human biological phantoms (i.e. solutions with equivalent electrical properties as the human body). The PI will build upon previous research in implantable integrated electronics and use advanced CMOS technology to bring forth fundamental advances in knowledge and innovation on miniature passive devices for in-body communications. Broader Impacts: A specific high-impact engineering application of a miniature passive device with integrated RF subsystem is in medication compliance monitoring, as it is estimated that the annual cost to the U.S. healthcare system from non-compliance with medication regimens exceeds $100 billion. The proposed plan is intended to promote interest in multidisciplinary research that will provide graduate, undergraduate and high school students exposure to innovative integrated circuit technologies. The proposed educational plan will emphasize the participation of underrepresented groups at the high school level via educational modules with theoretical and experimental components in the integrated research and academic programs.