Multiple Metal-Carbon Bonds, Metallacycles, and Catalytic Reactions

麻省理工学院的Richard R. Shrock教授得到了无机、生物无机和有机金属化学项目的支持，研究了用钼和钨的亚胺烷基基配合物进行不对称烯烃复分解的合成和机理。由催化剂分解形成的相关非桥接M=M双核配合物的基本反应也在探索中。绘制能量表面的形成和重排的金属环丁烷中间体是中心的烯烃的反应是这个程序的目标。有点像广场舞舞伴的变化，烯烃复分解涉及结合两种烯烃，以经济有效的方式产生两种新的烯烃。为了提高早期过渡金属配合物的催化性能，研究了其高氧化态有机金属化学。这些试剂对于有机底物的催化转化是重要的，特别是那些合成手性药物产品所需的试剂。

Professor Richard R. Shrock of the Massachusetts Institute of Technology is supported by the Inorganic, Bioinorganic and Organometallic Chemistry program to develop synthetic and mechanistic aspects of asymmetric olefin metathesis with imido alkylidene complexes of molybdenum and tungsten. Fundamental reactions of related unbridged M=M dinuclear complexes, formed from catalyst decomposition, are also being explored. Mapping energy surfaces for formation and rearrangement of metallacyclobutane intermediates that are central to olefin metathesis reactions is a goal of this program.Somewhat like a square dance partner change, olefin metathesis involves combining two olefins to yield two new olefins in an economically efficient manner. High oxidation state organometallic chemistry of early transition metal complexes is being investigated in order to improve their catalytic capabilities. These reagents are important for catalytic transformations of organic substrates, particularly those needed for the synthesis of chiral pharmaceutical products.