MRI: Acquisition of a Mass Spectrometer System for Undergraduate Research at the University of St. Thomas and Associated Colleges of the Twin Cities

圣托马斯大学(UST)将从主要研究仪器项目获得离子陷阱液相色谱质谱计(ION Trap LC-MS)系统。该仪器将使双城联合学院(科大、麦卡莱斯特学院、奥格斯堡学院和汉姆林大学)的研究人员能够研究：i.)新的光致变色化合物、同位素标记药物和新抗生素的合成；新型环番化合物和过渡金属介导的大环、笼状配合物的合成与表征；天然水中抗生素的光降解产物；四)使用微渗析探头监测大气气溶胶和系统的化学。其他高级人员将利用该仪器进行材料化学、有机合成、法医化学、药物化学、神经科学和植物生理学的研究。质谱学是化学家使用的标准工具，通过准确测量材料和化学物种在仪器中蒸发和电离时的质量和碎裂模式来识别和表征它们。液相色谱是一种分离技术，在将复杂的混合物引入质谱仪之前，将其分离成单独的组分。这项收购将供本科生在研究项目中动手使用。还将在实验室课程教学中向学生介绍分析技术。

The University of St. Thomas (UST) will acquire an ion trap liquid chromatograph mass spectrometer (ion trap LC-MS) system with this award from the Major Research Instrumentation program. The instrument will enable researchers at the Associated Colleges of the Twin Cities (UST, Macalester College, Augsburg College, and Hamline University) to study: i.) the synthesis of novel photochromic compounds, isotopically-labeled drugs, and new antibiotics; ii.) the synthesis and characterization of novel cyclophanes and transition metal-mediated macrocyclic and cage complexes; iii.) photodegradation products of antibiotics in natural waters; iv.) the chemistry of atmospheric aerosols and systems being monitored using microdialysis probes. Other senior personnel will utilize the instrument for research in materials chemistry, organic synthesis, forensic chemistry, medicinal chemistry, neuroscience, and plant physiology.Mass spectroscopy is a standard tool used by chemists to identify and characterize materials and chemical species by accurate measurement of their mass and fragmentation patterns as they are vaporized and ionized in the instrument. Liquid chromatography is an isolation technique that separates a complex mixture into individual components before introduction to the mass spectrometer. This acquisition will be used hands-on by undergraduate students in research projects. Students will also be introduced to the analysis technique in laboratory course instruction.