Multi-Catalyst Systems: Non-covalent Bifunctional Catalytic Complexes

该项目将继续致力于开发将两种或多种催化剂结合在一个系统中的方法，目标是使已知反应更快，更具选择性，并实现新的反应。 虽然现有的多催化剂系统以较低的成本产生更有效和选择性的反应，但它们目前的范围是有限的。 通过将它们的用途扩大到更多的反应，预计将在整个合成领域产生重大效益。 该项目的重点是双功能催化剂（在一个分子中具有两种催化特性），它可以导致更快的反应速率，更大的对映体和化学选择性以及更好的产率。有了这个奖项，有机和大分子化学计划支持D教授的研究。佛罗里达州立大学化学系的泰勒McQuade说。 McQuade教授的研究工作围绕着多催化剂系统的开发。 全世界生活水平的提高导致对拯救生命的小分子的需求增加，但能源和原材料成本的上升威胁到这些分子的获取。 拟议工作的成功将导致合成效率的进步和显着加快的反应速率，这将有助于满足全球对这些重要分子的需求

This project will continue work on the development of methods that combine two or more catalysts in one system with the goal of making known reactions faster and more selective and also enabling new reactions. While existing multi-catalyst systems yield more efficient and selective reactions at less expense, their current range is limited. By broadening their use to even more reactions, significant benefits across the field of synthesis are expected. This project focuses on bifunctional catalysts (with two catalytic features in one molecule), which can lead to faster reaction rates with greater enantio- and chemoselectivity as well as better yields.With this award, the Organic and Macromolecular Chemistry Program is supporting the research of Professor D. Tyler McQuade of the Department of Chemistry at Florida State University. Professor McQuade's research efforts revolve around the development of multi-catalyst systems. The rising standard of living worldwide has resulted in greater demand for life-saving small molecules, but access to these molecules is threatened by rising costs of energy and raw materials. Success of the proposed work would lead to advances in synthetic efficiency and significantly accelerated reaction rates that would help to satisfy the global demand for these important molecules