MRI: Acquisition of Integrated Small and Wide Angle X-ray Scattering Instrumentation for the Rocky Mountain Region

摘要：所要求的集成2D-SAXS/WAXS仪器将作为北方科罗拉多落基山脉地区学术机构的共享资源。其中包括五所主要的研究型大学（科罗拉多州立大学（CSU）、科罗拉多大学、科罗拉多矿业学院、丹佛大学和怀俄明州大学）和两个国家实验室（NREL和NIST？#21453;，一个小时内全部？CSU的半径。集成的2D-SAXS/WAXS仪器将被安置在CSU的共享多用户中央仪器设施（CIF）中，这是一个24小时开放的设施，供受过培训的用户使用。该仪器预计将立即使用的研究小组的21名教师来自10个部门跨越这些大学中的四个。其中有八个新的教师，当地获得综合2D-SAXS/WAXS将在他们新兴的研究项目的发展中发挥决定性作用。集成的2D-SAXS/WAXS仪器将用于分析各种各样的研究项目。例子包括纳米结构水凝胶网络和有机光伏材料的开发;立体和DNA样嵌段共聚物的形态表征;从可聚合溶致液晶开发纳米过滤和反渗透膜; RNA折叠在翻译和其他生物活动中的机制和作用;结构对过渡金属纳米颗粒纳米簇的稳定性、催化活性和寿命的作用;关节置换技术的机械和磨损性能的改善;从可再生聚合物组合物合成生物活性材料;以及使用可再生聚合物产生聚合物复合材料。这一工具的独特性，该地区，与CIF的开放获取政策相结合，将发挥关键作用，最大限度地提高我们的能力，发展与未来的学生和教师来自该地区各地的关系，包括少数民族服务机构在科罗拉多其中CIF的使用在CSU鼓励通过100%补贴。摘要为非技术观众纳米科学和纳米技术研究在北方科罗拉多落基山脉地区在过去十年中迅速增长，在五个主要研究型大学（科罗拉多州立大学，科罗拉多大学，科罗拉多矿业学院，丹佛大学和怀俄明州大学），两个国家实验室（NREL和NIST？博尔德），和政治倡议，吸引新兴的纳米技术公司，使科罗拉多他们的家。本提案中寻求的集成小角度和广角X射线散射仪器将安装在CSU的多用户中央仪器设施（CIF）内，并在区域间公开共享，以推进这些机构中跨越10个不同部门的21多名教师的研究计划;研究项目正在开发下一代材料，用于丰富多样的应用，包括有机太阳能电池，水过滤膜，化学和药物输送、纳米颗粒催化剂、关节置换技术、可再生聚合物复合材料、人造肌肉和组织生长支架。我们预计对关键基础设施目标和项目的直接和重大影响符合CSU？我们的教育使命是追求卓越和教学创新，特别是我们积极努力扩大科学和工程领域代表性不足的群体的参与。这一工具的独特性，加上CIF的开放获取政策，将在发展与来自整个区域的未来学生和教师的关系方面发挥关键作用，包括几个非常重要的少数民族服务机构，CIF中的所有工具的使用都是严格免费的。 此外，在我们的研究和课程为基础的教育机制，包括这种工具将确保我们的研究生和本科生培训计划是先发制人地适应技能集的要求与科罗拉多一致？不断变化的经济格局。

Abstract for a Technical AudienceThe integrated 2D-SAXS/WAXS instrumentation requested will serve as a shared resource for the academic institutions of the Northern Colorado Rocky Mountain region. These include five major research universities (Colorado State University (CSU), University of Colorado, Colorado School of Mines, Denver University, and University of Wyoming) and two national labs (NREL and NIST ? Boulder), all within an hour?s radius of CSU. The integrated 2D-SAXS/WAXS instrument will be housed in the shared multi-user Central Instrument Facility (CIF) at CSU, a 24-hour open access facility for trained users. This instrumentation is expected to have immediate usage by the research groups of 21 faculty originating from 10 departments spanning four of these universities. Among these are eight new faculty for which local access to integrated 2D-SAXS/WAXS would play a deciding role in the development of their emerging research programs. The integrated 2D-SAXS/WAXS instrumentation will be applied to the analysis of a tremendously varied collection of research projects. Examples include the development of nanostructured hydrogel networks and organic photovoltaic materials; the characterization of morphology in stereo and DNA-like block copolymers; the development of nanofiltration and reverse osmosis membranes from polymerizable lyotropic liquid crystals; the mechanisms and roles of RNA folding in translation and other biological activities; the role of structure on stability, catalytic activity, and lifetime of transition-metal nanoparticle nanoclusters; the mechanical and wear property improvement of joint replacement technologies; the synthesis of biologically active materials from polyelectrolyte assemblies; and the generation of polymer composites using renewable polymers. The uniqueness of this instrument to the region, combined with the open-access policies of the CIF will play a key role in maximizing our ability to develop relationships with prospective students and faculty from all over the region, including minority serving institutions in Colorado for which CIF usage at CSU is encouraged through 100% subsidy. Abstract for a Non-Technical AudienceNanoscience and nanotechnology research in the Northern Colorado Rocky Mountain region has grown intensely in the last decade, spurred on by the research activities at five major research universities (Colorado State University, University of Colorado, Colorado School of Mines, Denver University, and University of Wyoming), two national labs (NREL and NIST ? Boulder), and political initiatives that entice emerging nanotechnology companies to make Colorado their home. The integrated small and wide angle X-ray scattering instrumentation sought in this proposal will be housed within the multi-user Central Instrument Facility (CIF) at CSU, and openly shared among region to advance the research programs of over 21 faculty spanning 10 different departments across these institutions; research programs that are developing next-generation materials for a rich and diverse collection of applications, including organic solar cells, water filtration membranes, chemical and drug delivery, nanoparticle catalysts, joint replacement technologies, renewable polymer composites, artificial muscles and tissue growth scaffolds. We anticipate a direct and significant impact on key infrastructural goals and projects consistent with CSU?s educational mission for excellence and innovation in teaching, and in particular our active efforts to broaden participation of underrepresented groups in the sciences and engineering. The uniqueness of this instrument, combined with the open-access policies of the CIF will play a key role in developing relationships with prospective students and faculty from all over the region, including several very important minority serving institutions for which use of all instrumentation in the CIF is strictly gratis. In addition, the inclusion of this instrument in our research and curricular based education mechanisms will ensure our graduate and undergraduate training programs are preemptively adapting to skill set demands consistent with Colorado?s changing economic landscape.