Synthesis, Reactivity and Mechanisms of Group 4 Metallocene Catalysts

无机化学、生物无机化学和金属有机化学计划支持芝加哥大学理查德·F·乔丹教授的研究，以设计合成对映体4族茂金属的一般方法和用于不对称催化的新型催化剂的库。新的手性茂金属化合物使新的催化、立体选择性的C-H功能化反应的发展成为可能，这些反应可以应用于有机合成和主链中含有杂环的新型聚合物的合成。对d0-金属烯烃和烯烃配合物的研究为这些物种的结构、热力学、动力学、动力学性质和插入机理提供了新的见解。手性化合物的合成在医药和聚合物化学工业中具有重要意义。该项目为芝加哥大学、莱克福里斯特学院和其他芝加哥地区的本科学校的本科生提供有价值的研究培训。该项目还通过芝加哥大学大学生学者计划，为芝加哥公立学校系统的高中生提供了令人兴奋的科学体验。

The Inorganic, Bioinorganic and Organometallic Chemistry Program supports the research of Professor Richard F. Jordan of the University of Chicago to design general methods for the syntheses of enantiopure group 4 metallocenes and libraries of the new catalysts for applications in asymmetric catalysis. The new chiral metallocenes enable the development of new catalytic, stereoselective C-H functionalization reactions that can be applied in organic syntheses and in the syntheses of novel polymers that contain heterocycles in the main chain. The studies of the d0-metal alkene and alkyne complexes provide new insights to the structures, thermodynamics, kinetics, dynamic properties, and insertion mechanisms of these species. The synthesis of chiral compounds is of critical importance in the pharmaceutical and polymer chemical industries. This project provides valuable research training for undergraduates at the University of Chicago, Lake Forest College, and other Chicago-area undergraduate schools. The project also offers exciting science experiences for high school students from the Chicago Public School system through the University of Chicago Collegiate Scholars Program.