课题基金 / 基金详情

MRI: Acquisition of a Molecular Imaging Instrument for Dynamic Material and Biological Systems

MRI: Acquisition of a Molecular Imaging Instrument for Dynamic Material and Biological Systems
MRI:获取用于动态材料和生物系统的分子成像仪器
批准号:
0922539
负责人:
Stephen Boppart
金额:
$177.09万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-09-01 至 2013-08-31

项目摘要

项目成果

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中文摘要
翻译
该奖项是根据2009年《美国复苏和再投资法案》(公法111-5)资助的。获得和使用这种分子成像仪器将带来新的研究方向、教育机会和项目,这些将对这些不同但统一的领域的知识基础做出重大贡献,并在国家和国际层面上做到这一点。这五个研究领域包括:(1)监测先进的自我修复材料内的动态化学反应;(2)跟踪纳米颗粒的生物分布并可视化地将其整合到活体的生理过程中;(3)跟踪干细胞的归巢途径及其功能意义;(4)研究代谢组学以了解营养的生物学和生理学基础;(5)监测环境样品中材料、化学物质和微生物的动态三维分布。这一分子成像仪器的收购不仅将使现有研究计划迅速扩大,还将为新的研究方向提供机会。
英文摘要
0922539Boppart"This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5)."The acquisition and use of this molecular imaging instrument will enable new research directions and educational opportunities and programs that will significantly contribute to the intellectual base of knowledge in these disparate but unified areas, and do so on national and international levels. The five research areas include (1) monitoring dynamic chemical reactions within advanced self-healing materials, (2) tracking nanoparticle biodistribution and visualizing their incorporation into the physiological processes of living organisms over time, (3) following the homing pathways of stem cells and their functional significance, (4) investigating metabolomics to understand the biological and physiological basis of nutrition, and (5) monitoring the dynamic three-dimensional distributions of materials, chemicals, and microbes in environmental samples. The acquisition of this molecular imaging instrument will not only enable the rapid expansion of existing research programs, but also provide the opportunity for new directions of investigation.
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