Department of Chemistry Laboratory Renovation in Support of Faculty-Student Research

该奖项是根据2009年美国复苏和再投资法案(公法111-5)资助的。该项目的目标是翻新高露洁大学永利大厅的实验室空间。永利堂此前曾被用于教学和研究。拟议的翻修将创建两个私人生化研究实验室和一个共享的生物化学/分子生物学设施，用于研究和研究培训。此外，还提议建立一个共享的计算机建模和模拟设施以及一个新的激光实验室。五名教员、一名博士后和许多本科生将在拟议的设施中进行各种生化主题的研究，包括碳酸氢酶催化和变构的结构和功能研究；光合蛋白的化学修饰；C-连接糖肽的合成和构象评估；六元环的气相构象；以及模型对流层气溶胶颗粒表面的光谱、结构和动力学。PIS有很好的出版记录，包括作者名单中的本科生。该项目将加强研究的基础设施，特别是学生和教职员工之间的合作项目。新修订的课程增加了专业的数量，改建后的设施将成为吸引学生学习化学的动力。

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).The goal of this project is to renovate laboratory space in Wynn Hall at Colgate University. Wynn Hall has previously been used for teaching and research. The proposed renovation will create two private biochemical research laboratories and a shared biochemistry/molecular biology facility to be used for research and research training. In addition, a shared computer modeling and simulation facility and a new laser laboratory are being proposed. Five faculty members, one postdoc, and numerous undergraduate students will conduct research in the proposed facility on a variety of biochemical topics, including structural and functional studies of catalysis and allostery in carbonic anhydrase; chemical modification of photosynthetic proteins; C-linked glycopeptide synthesis and conformer evaluation; gas phase conformation of six-membered rings; and spectroscopy, structure, and dynamics of model tropospheric aerosol particle surfaces. The PIs have a strong publication record including undergraduate students in the author lists.The project will enhance infrastructure for research and in particular collaborative projects between students and faculty. The newly revised curriculum led to an increased number of majors, and the remodeled facilities will serve as a motivator to attract students to chemistry.