2010 Gordon Research Conference on the Biology Post-Transcriptional Gene Regulation to be held July 18 through July 23, 2010; Newport, R.I.

关于“转录后基因调控生物学”的戈登研究会议（GRC）将于2010年7月18日至7月23日在罗德岛州新港的萨尔维里贾纳大学举行。此次会议是自2004年以来每两年举行一次的GRC系列会议中的第四次会议。本系列的目的是阐明RNA生物发生的基本机制和调控。重点是涉及mRNA的产生和代谢的转录后交易，但这延伸到转录偶联，以及涉及翻译及其控制的因素，包括tRNA和非编码（如微）rna。代表转录后基因调控的关键领域，演讲者将包括该领域的一些国际知名专家，以及根据其提交的摘要内容选择的更多初级演讲者。预计约有150名与会者参加为期五天的会议。该计划将包括9个上午或晚上的会议，广泛解决转录和RNA加工之间耦合领域的前沿问题；rna加工信号和因子的基因组学和进化；RNA剪接催化、保真度和调控；RNA周转，包括无义介导的mRNA衰变；RNA转运和定位；非编码RNA;平移控制;以及rna -蛋白相互作用。此外，四个小型海报会议将使所有参与者都能对这些主题做出贡献并了解这些主题。在Salve Regina大学相对孤立的夏季环境中，免费的午后和傍晚时间应该激发成熟的和更多的初级研究人员，博士后实习生以及来自美国和国外的研究生之间富有成效的非正式讨论。这个戈登研究会议有一个独特的形式，汇集了研究人员的集合-研究生，博士后研究员，在所有的职业生涯阶段的主要研究人员，拨款管理人员，科学家从制药和出版行业，尽管有共同的兴趣，很少有机会见面作为一个群体。由此产生的智力交流将有助于确定关键领域，从而有助于推动这一领域向前发展。了解转录后基因调控的基本机制对于全面了解基因组的组织、功能和进化至关重要。本次会议的发言人包括17名女性和5名未被充分代表的少数民族。从申请者中挑选参加者将采用针对少数民族、妇女和青年科学家的平权行动原则。美国国家科学基金会将资助在美国实验室工作的年轻研究人员，包括研究生、博士后研究员和初级首席研究人员。

The Gordon Research Conference (GRC) on "The Biology of Post-Transcriptional Gene Regulation" will be held at Salve Regina University in Newport, Rhode Island, from July 18th to July 23rd, 2010. This meeting is the fourth in a GRC series that has been held every other year since 2004. The goal of this series is the elucidation of the fundamental mechanisms and regulation of RNA biogenesis. The emphasis is on post-transcriptional transactions involving the generation and metabolism of mRNA, but this extends to transcriptional coupling, and to factors involved in translation and its control, including tRNA and non-coding (e.g., micro) RNAs. Representing key areas of post-transcriptional gene regulation, the speakers will include a number of internationally known experts in this field, along with more junior speakers chosen on the basis of the content of their submitted abstracts. Approximately 150 participants are expected for the five-day meeting. The program will consist of nine morning or evening sessions that broadly address cutting-edge issues in the areas of coupling between transcription and RNA processing; genomics and evolution of RNA-processing signals and factors; RNA splicing catalysis, fidelity, and regulation; RNA turnover, including nonsense-mediated mRNA decay; RNA transport and localization; non-coding RNA; translational control; and RNA-protein interactions. In addition, four small poster sessions will enable all participants to contribute to, and learn about, these topics. Free early-afternoon and late-evening periods in the relatively isolated summer setting of Salve Regina University should stimulate productive, informal discussions among established and more junior investigators, postdoctoral trainees, and graduate students from the U.S. and abroad. This Gordon Research Conference has a unique format that brings together sets of researchers - graduate students, post-doctoral fellows, principal investigators at all career stages, grant administrators, scientists from the pharmaceutical and publishing industries who, despite converging interests, have only infrequent opportunities to meet as a group. The resulting intellectual cross-fertilization will help define critical areas and thus help propel this field forward. Understanding the basic mechanisms of post-transcriptional gene regulation is essential for a full understanding of the organization, function, and evolution of genomes. Speakers for this conference include 17 females and five underrepresented minorities. The selection of attendees from the pool of applicants will employ the principles of affirmative action with respect to minorities, women, and junior scientists. Funds from the National Science Foundation will support the attendance of young investigators working in U.S. laboratories, including graduate students, post-doctoral fellows, and beginning principal investigators.