Travel Support for ACS Symposium "Engineering the Cell-Material Interface", March 24-25, 2010 in San Fransico, California.

1021403 VanTassel作为第239届美国化学学会全国会议（2010年3月24-25日）的一部分，正在组织一个为期两天的专题讨论会，题为“细胞材料界面工程”。学术成就：研讨会的目的是突出材料表面工程在控制细胞附着、迁移、增殖、组装和功能方面的最新进展。一个关键的主题是通过界面化学，刚性，形貌，图案化和生物活性控制细胞行为，并将展示结合生物化学界面表征和细胞测定的论文。为了最大限度地扩大这次专题讨论会的影响，请求提供资金，支持来自国外的三位知名学者参加：（帝国理工学院，伦敦，英国）将发言工程细胞材料界面再生医学，伯努瓦Ladoux（法国巴黎狄德罗大学）将在微加工基板上发表演讲：这是研究微环境对细胞粘附和迁移影响的有用工具，Pierre Schaaf（法国斯特拉斯堡查尔斯萨德隆研究所）将就生物医学应用中的机械响应薄膜发表演讲。此外，还邀请了另外三位发言者，他们的支持将来自其他来源。这些演讲者包括加州伯克利分校的Kevin Healy教授、斯坦福大学的Annelise巴伦教授和法国Cergy-Ponte的Emmanuel Pauthe教授。Schaaf教授将在更基础的层面上介绍与薄膜组装和应用相关的重要软物质概念，并从更理论的角度探索多层薄膜的一些有趣的技术可能性。Ladouxs教授的谈话重点是表征由于细胞运动而在基底内发生的应力及其对细胞的影响，这将为随后的谈话创造一个理想的背景，重点是细胞基底的化学和结构特性，以及它们对接触细胞的影响。Stevens教授的演讲预计将从研讨会早些时候的基础科学重点演讲（表面功能化，细胞对特定表面的反应）过渡到那些专注于医学应用的演讲。所有这三个将有助于吸引观众，否则预计不会出席。所有研讨会与会者，特别是许多年轻的参与者（学生，博士后，初级教师）将受益于与这些领先的国际专家在为期两天的研讨会的互动。事实上，27个贡献的演讲中有几个将由学生和博士后提供。希望将国际领先的学者与美国科学家的未来结合起来，可能会导致未来的合作和/或交流努力。研讨会本身预计将通过提供一个论坛，在细胞材料相互作用的基础科学的进展，从不同背景的研究人员（化学，胶体，生物材料），可能会在生物医学的新应用的背景下进行讨论，产生广泛的影响。特别是，研讨会可能对组织工程和再生医学产生广泛的影响。

1021403Van TasselA two day symposium is being organized as part of the 239th American Chemical Society National Meeting (March 24-25, 2010) entitled "Engineering the Cell Material Interface". Three leading international scholars have been invited, for whom international travel support is requested.Intellectual Merit: The goal of the symposium is to highlight recent advances in material surface engineering to control cell attachment, migration, proliferation, assembly, and function. A key theme is control of cell behavior through interfacial chemistry, rigidity, topography, patterning, and bioactivity and papers combining physic chemical interfacial characterization with cellular assay are to be show cased. In order to maximize the impact of this symposium, funds are requested to support the participation of three eminent scholars from abroad: Molly Stevens (Imperial College, London, UK) will speak on Engineering the cell material interface for regenerative medicine, Benoit Ladoux (University of Paris Diderot, France) will speak on Microfabricated substrates: a useful tool to study the influence of microenvironments on cell adhesion and migration, and Pierre Schaaf, (Institut Charles Sadron, Strasbourg, France) will speak on Mechanically responsive films for biomedical applications. In addition, three other speakers have also been invited whose support will come from other sources. These speakers include Prof. Kevin Healy of California-Berkeley, Prof. Annelise Barron of Stanford, and Prof. Emmanuel Pauthe of Cergy-Pontoise (France).Broader Impact:Participation by the three individuals listed above will have a significant impact on the symposium. Prof. Schaaf will introduce, at a more fundamental level, important soft matter based concepts relevant to film assembly and application, and explore some interesting technological possibilities of multilayer films, from a more theoretical perspective. Prof. Ladouxs talk with it's focus on characterizing the stresses occurring within the substrate due to cell motion and their influence of the cells will create an ideal backdrop for subsequent talks focusing on chemical and structural properties of cell substrates, and their influence on contacting cells. Prof. Stevens talk is expected to make the transition from the basic science focused talks given earlier in the symposium (surface functionalization, cell responses to specific surfaces), to those focusing on medical applications. All three will help attract audience members otherwise not expected to attend. All symposium attendees but in particular many younger participants (students, postdocs, junior faculty) will benefit through interactions with these leading international experts over the two day symposium. In fact, several of the 27 contributed talks will be given by students and postdocs. It is hoped that mixing leading international scholars with up and coming US scientists may lead to future collaborative and/or exchange efforts. The symposium itself is expected to have a broad impact by providing a forum where advances in basic sciences of cell material interactions, from researchers with diverse backgrounds (chemistry, colloids, biomaterials), may be discussed in the context of new applications in biomedicine. In particular, the symposium could have a broad impact on tissue engineering and regenerative medicine.