Stochastic methods in chemistry and biophysics

加州大学圣巴巴拉分校的Frank Brown获得了化学学部（MPS/CHE）和分子与细胞生物学学部（BIO/MCB）化学理论、模型和计算方法项目的奖励，以开发用于模拟复杂生化和生物物理现象的脂质双层和生物膜的理论工具。布朗博士的算法允许在“介观”长度尺度（几十纳米到几十微米）和时间尺度（几十纳秒到几十秒甚至更长）范围内对非均匀膜表面进行流体动力学和热力学一致的建模。这项研究对实验的解释产生了广泛的影响，增强了我们对生物现象的理解，如膜蛋白在复杂细胞环境中的扩散以及人类红细胞的结构和动力学。布朗博士通过参加UCSB的物理马戏团和化学推广项目，向小学生传达科学的兴奋和重要性。布朗博士还担任UCSB科学计算中心的联合主任，该中心负责监督和维护UCSB校园的共享科学计算设施，用于研究和课堂教学。

Frank Brown of the University of California, Santa Barbara is supported by an award from the Chemical Theory, Models and Computational Methods program within the Division of Chemistry (MPS/CHE) and the Division of Molecular and Cellular Biology (BIO/MCB) for the development of theoretical tools to model lipid bilayers and biomembranes for use in simulating complex biochemical and biophysical phenomena. Dr. Brown's algorithms allow hydrodynamically and thermodynamically consistent modeling of inhomogeneous membrane surfaces over a range of "mesocopic" length scales (tens of nanometers to tens of microns) and time scales (tens of nanoseconds to tens of seconds and longer). The research is having a broad impact on the interpretation of experiments that enhance our understanding of biological phenomena such as the diffusion of membrane proteins in complex cellular environments and the structure and dynamics of human red blood cells. Dr. Brown communicates the excitement and importance of science to grade school children through his participation in the Physics Circus and Chemistry Outreach programs at UCSB. Dr. Brown also serves as co-director of the UCSB center for scientific computing, which oversees and maintains shared scientific computing facilities for the UCSB campus, for use in both research and classroom teaching.