Light Induced Enantiospecific Chiral Transfer In Solution

根据化学结构、动力学和机理计划(CSDM)的资助，北达科他州法戈州立大学化学和生物化学系西瓦鲁鲁·贾亚拉曼教授的团队将开展与溶液中光诱导的对映异构手性转移有关的研究。在光诱导转化过程中合成具有高立体选择性的手性化合物为开发对环境影响最小的可持续策略提供了机会。作为调查的一部分，PI将寻求光反应立体控制的新策略，以获得对光与物质相互作用的基本了解，以及对分子反应性、动力学和非键相互作用的复杂控制，以提高光产品的立体选择性。该项目发展计划无缝地整合了科学研究、教育培训和公众宣传。参与拟议研究的学生将学习传统技术来表征和评估对映异构光转化过程中的不对称诱导，以及现代光谱方法和表征技术来评估激发态反应性。PI计划通过他在北达科他州开发的野餐(父母与孩子的参与，培养科学的智力好奇心)推广计划来吸引当地高中生。该推广计划的目的是通过鼓励高中生将科学和数学作为职业道路，为他们提供一个尖端的研究环境。

Based on the funding from Chemical Structure, Dynamics and Mechanism Program (CSDM) program, Prof. Sivaguru Jayaraman's group at the Department of Chemistry and Biochemistry, North Dakota State University, Fargo, ND will carry out studies pertaining to light induced enantiospecific chiral transfer in solution. Synthesizing chiral compounds with high stereoselectivity during light induced transformations provides an opportunity to develop sustainable strategies with minimal impact on the environment. As part of the investigation the PI will pursue new strategies for stereocontrol in photoreactions to gain a fundamental understanding of interaction of light with matter coupled with an intricate control over molecular reactivity, dynamics and non-bonding interactions to enhance stereoselectivity in the photoproducts.The project development plan seamlessly integrates scientific research, educational training, and public outreach. Students involved in the proposed investigations will learn both traditional techniques to characterize and evaluate asymmetric induction during enantiospecific phototransformations and modern spectroscopic methods and characterization techniques to assess excited state reactivity. The PI plans to engage local high school students through the PICNICS (Parents Involvement with Children, Nurturing Intellectual Curiosity in Science) outreach program that he has developed at North Dakota. The aim of the outreach program is to provide a cutting edge research environment to high school students there by encouraging them to look up to science and math as career paths.