MRI: Acquisition of a Fluorescence Activated Cell Sorter (FACS)

这项提议是为了收购最先进的荧光激活细胞分选器(FACS)，该分选器将成为流式细胞仪/细胞分选共享使用设施的一部分，以吸引俄克拉荷马大学诺曼分校(OU)校园内的各种研究项目。细胞分选被认为是从生命科学的基础生物学到转译生物医学工程研究等领域的重要和不可或缺的工具。在俄勒冈大学诺曼校区收购最先进的细胞分选能力不仅将提供所需的资源，还将为俄勒冈大学诺曼校区现有的细胞表征设施提供强大的补充：扫描电子显微镜、多光子激光扫描共焦显微镜和原子力显微镜。将这些显微镜技术提供的关于单个细胞结构的详细信息与(I)来自高通量流式细胞仪的关于细胞群体的广泛统计信息以及(Ii)通过免疫表型从复杂群体中识别和分类细胞的能力相结合，将在整个俄勒冈大学园区培养新的创新研究方向。

This proposal is for the acquisition of a state-of-the-art Fluorescence Activated Cell Sorter (FACS) that will become part of a flow cytometry/cell sorting shared use facility appealing to a diverse set of research programs on the University of Oklahoma (OU) campus in Norman. Cell sorting is recognized as important and indispensable tools in fields ranging from basic biology in the life sciences to translational biomedical engineering research. Acquisition of state-of-the-art cell sorting capabilities on the OU-Norman campus would not only make available needed resources, but would also provide a powerful complement to existing cellular characterization facilities on the OU-Norman Campus: Scanning Electron Microscopy, Multi-photon Laser Scanning Confocal Microscopy, and Atomic Force Microscopy. Combining detailed information about individual cell structures provided by these microscopy techniques with (i) the extensive statistical information about cell populations from high throughput flow cytometry and (ii) the ability to identify and sort cells from complex populations by immunophenotyping will foster new and innovative research directions across the OU campus.