CAREER: Ultrahigh-Frame-Rate Compressively-Sensed Imaging using Ultrafast Lasers

目的：该计划的目标是通过开发一种结合了压缩传感优点的光子成像体系结构来克服当前超高帧速率光学成像的局限性。智能化的优点：当前创纪录的高帧速率光学成像体系结构严重负担着传输和记录大量信息的需要。该计划将通过使用专门为压缩传感设计的光子成像架构，对最先进的方法进行变革性的改进；将数据压缩直接构建到测量过程中。因此，这种新的架构将在大大减少信息容量要求的同时提高信号强度，实现高速图像采集，并将形成应用于所有科学技术领域的新一代超高帧频成像系统。更广泛的影响：更广泛的影响是，最近对高速成像的研究表明，将超高帧频成像纳入流式细胞术将大大增加从测量中提取的信息量。这对于识别在基本健康的人群中存在极其罕见的疾病预测细胞等应用至关重要。这种应用可以通过改进医疗诊断对社会产生广泛影响，并将成为本研究计划的重点。此外，该计划将通过为高中生和本科生开展动手实验室活动，开设新的本科生光子学入门课程，以及为本科生和研究生举办研讨会和海报会议来获得传播研究的经验，从而使PI的教育目标受益。

Objective:The objective of this program is to overcome the current limitations in ultrahigh-frame-rate optical imaging through the development of a photonic imaging architecture that incorporates the benefits of compressive sensing.Intellectual Merit:The intellectual merit is that current record-high frame-rate optical imaging architectures are severely burdened by the need to transfer and record massive amounts of information. This program will make transformative advancements to the state-of-the-art approach through the use of a photonic imaging architecture designed specifically for compressive sensing; building data compression directly into the measurement process. Thereby, this new architecture will enable high-speed image acquisition with a greatly reduced information capacity requirement as well as increased signal strength and will form a new generation of ultrahigh-frame-rate imaging systems for use in all areas of science and technology.Broader Impact:The broader impacts are that recent research into high-speed imaging suggests that the incorporation of ultrahigh-frame-rate imaging into flow cytometry will greatly increase the information extracted from the measurements. This is critical to applications such as identifying the presence of extremely rare disease-predicting cells within a largely healthy population. Such an application can have a broad impact on society through improved medical diagnostics and will be a focus of this research program. Additionally, the program will benefit the educational objectives of the PI through the development of hands-on laboratory activities for high school and undergraduate students, a new introductory undergraduate photonics course, and seminars and poster sessions for undergraduate and graduate students to gain experience disseminating their research.