Molecular probes for pancreatic cancer

在澳大利亚，癌症已经取代心脏病成为过早死亡的主要原因。目前，每两名男性中就有一名被诊断患有癌症，每三名女性中就有一名被诊断患有癌症。胰腺癌是澳大利亚癌症死亡的第四大原因，目前缺乏有效的治疗方法导致一年生存率略高于10%，五年生存率不到5%。本项目旨在鉴定和生产具有新的作用机制的新化合物，以促进我们对胰腺癌发生的了解，并为开发新的治疗策略提供基础。未来被诊断为胰腺癌的澳大利亚人可能会直接受益于这项工作的结果。

Cancer has overtaken heart disease as the main cause of premature death in Australia. Currently one in two men and one in three women are diagnosed with cancer during their lifetime. Pancreatic cancer is the fourth leading cause of cancer death in Australia, and the current lack of effective therapies results in a 1 year survival of just over 10%, and a 5 year survival of less than 5%. This project aims to identify and produce new compounds with novel mechanisms of action that will facilitate our understanding of pancreatic carcinogenesis and provide the basis for the development of new therapeutic strategies. Australians diagnosed with pancreatic cancer in the future may directly benefit from the results of this work.