Exploring Ionic Liquids in Sample Preparation and Multidimensional Chromatographic Separations

托莱多大学的Jared L.Anderson教授在化学系化学测量和成像(CMI)计划的支持下，探索离子液体作为分离介质在层析和微萃取中的应用。该项目将提供有关离子液体如何影响分析物的差示萃取及其通过各种色谱技术进行分离和分析的新知识，并将扩大离子液体在实际化学和生物样品分析中的适用范围。分析化学以外的其他领域的一个主要影响是开发了分析复杂流体的技术，如从生物质中提取的石油和燃料。安德森教授和他的研究团队将在分离科学中离子液体的保护伞下进行三个不同的倡议。磁性离子液体将用于脱氧核糖核酸的选择性萃取和长期储存；聚合物离子液体将被开发为单壁碳纳米管并用作固相微萃取的吸附涂层；离子液体将被开发用于多维气相色谱的选择性固定相。在进行这项研究的过程中，研究生和本科生将获得分离科学和层析方面的宝贵技能，并将开发基于Facebook的社交网络扩展计划，向幼儿和普通公众展示科学概念。

Professor Jared L. Anderson of the University of Toledo is supported by the Chemical Measurement and Imaging (CMI) Program in the Division of Chemistry to explore the application of ionic liquids as separation media in chromatography and microextractions. The project will provide new knowledge on how ionic liquids effect the differential extraction of analytes and their separation and analysis by various chromatographic techniques, and will expand the scope of applicability of ionic liquids in the analysis of real chemical and biological samples. A major impact across fields other than analytical chemistry is in the development of techniques for the analysis of complex fluids such as oils and fuels derived from biomass. Professor Anderson and his research team will conduct three separate initiatives under the umbrella of ionic liquids in separation science. Magnetic ionic liquids will be studied in the selective extraction and long term storage of deoxyribonucleic acid; polymeric ionic liquids, incorporating single-walled carbon nanotubes, will be developed and used as sorbent coatings for solid-phase microextraction; and ionic liquids will be developed and used as selective stationary phases for multidimensional gas chromatography. In the course of conducting this research, graduate and undergraduate students will acquire valuable skills in separation science and chromatography, and Facebook-based social networking outreach programs will be developed to present scientific concepts to young children and the general public.