The role of electrostatic charge in airway deposition of aerosols
The role of electrostatic charge in airway deposition of aerosols
批准号:
DP160102577
负责人:
Prof Hak-Kim Chan
金额:
$26.07万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-03-01 至 2019-06-30
中文摘要
该项目旨在揭示静电电荷在控制呼吸道内气雾剂沉积方面的重要性。预期的结果是一个经过验证的数学模型,用于准确预测带电气溶胶粒子在人类呼吸道中的沉积行为。这些发现最终可能被用来支持新的预防措施,以减少吸入的有害空气颗粒物的肺沉积,从而显著降低健康风险和成本。它们还可用于开发基于静电的新吸入技术,以改善对呼吸系统疾病患者肺部的气雾剂药物输送。
英文摘要
This project aims to unravel the importance of electrostatic charge in controlling deposition of aerosols in the respiratory tract. The expected outcome is a validated mathematical model for accurately predicting deposition behaviour of charged aerosol particles in human airways. Findings may ultimately be used to underpin novel prevention measures to reduce lung deposition of inhaled hazardous airborne particles to significantly reduce health risks and costs. They may also be used to enable the development of new inhalation technologies based on electrostatic charge to improve aerosol drug delivery to the lungs of patients with respiratory diseases.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Unravelling the mechanics of particle deposition at the micro-scale
-
批准号:DP220100764
-
项目类别:Discovery Projects
-
资助金额:$35.61万
-
财政年份:2022
-
负责人:Prof Hak-Kim Chan
-
依托单位:
Understanding bacteriophage deactivation and stabilisation in formulations
-
批准号:DP210102526
-
项目类别:Discovery Projects
-
资助金额:$38.03万
-
财政年份:2021
-
负责人:Prof Hak-Kim Chan
-
依托单位:
A novel approach for the real-time measurement of aerosol surface area
-
批准号:LP190100511
-
项目类别:Linkage Projects
-
资助金额:$25.52万
-
财政年份:2020
-
负责人:Prof Hak-Kim Chan
-
依托单位:
High-load powder dispersion and aerosol delivery: an integrated approach
-
批准号:LP190100842
-
项目类别:Linkage Projects
-
资助金额:$32.82万
-
财政年份:2020
-
负责人:Prof Hak-Kim Chan
-
依托单位:
Particle transport in the human upper airway
-
批准号:DP190101237
-
项目类别:Discovery Projects
-
资助金额:$33.97万
-
财政年份:2019
-
负责人:Prof Hak-Kim Chan
-
依托单位:
Novel nano-composite particles for controlled-release drugs via inhalation
-
批准号:LP160101498
-
项目类别:Linkage Projects
-
资助金额:$36.12万
-
财政年份:2018
-
负责人:Prof Hak-Kim Chan
-
依托单位:
Enabling aerosol delivery of phages to defeat antibiotic-resistant bacteria
-
批准号:DP150103953
-
项目类别:Discovery Projects
-
资助金额:$37.71万
-
财政年份:2015
-
负责人:Prof Hak-Kim Chan
-
依托单位:
Production of nano-composite particles for inhalational delivery of combination drugs
-
批准号:DP120102778
-
项目类别:Discovery Projects
-
资助金额:$22.91万
-
财政年份:2012
-
负责人:Prof Hak-Kim Chan
-
依托单位:
Developing novel aerosol inhalers for pulmonary drug delivery from the fundamental understanding of powder dispersion mechanisms
-
批准号:DP110105161
-
项目类别:Discovery Projects
-
资助金额:$17.94万
-
财政年份:2011
-
负责人:Prof Hak-Kim Chan
-
依托单位:
The Scale-up and Evaluation of a Novel Dense Gas Technology Platform for the Production of Particles for Aerosol Drug Delivery.
-
批准号:LP0883969
-
项目类别:Linkage Projects
-
资助金额:$8.45万
-
财政年份:2009
-
负责人:Prof Hak-Kim Chan
-
依托单位:
Development of a novel process for the formation of particles with controlled surface architecture for respiratory drug delivery
-
批准号:DP0985367
-
项目类别:Discovery Projects
-
资助金额:$24.92万
-
财政年份:2009
-
负责人:Prof Hak-Kim Chan
-
依托单位:
Mannitol Powders for Assessment of Asthma in Children
-
批准号:LP0775441
-
项目类别:Linkage Projects
-
资助金额:$9.96万
-
财政年份:2007
-
负责人:Prof Hak-Kim Chan
-
依托单位:
Discrete particle simulation of powder dispersion in pharmaceutical aerosol inhalers
-
批准号:DP0773755
-
项目类别:Discovery Projects
-
资助金额:$20.1万
-
财政年份:2007
-
负责人:Prof Hak-Kim Chan
-
依托单位:
State-of-the-art high resolution thermal analysis suite for the life and material sciences
-
批准号:LE0775720
-
项目类别:Linkage Infrastructure, Equipment and Facilities
-
资助金额:$6.67万
-
财政年份:2007
-
负责人:Prof Hak-Kim Chan
-
依托单位:
High Gravity Precipitation of Nanoparticles for Pulmonary Drug Delivery
-
批准号:LP0561675
-
项目类别:Linkage Projects
-
资助金额:$25.46万
-
财政年份:2006
-
负责人:Prof Hak-Kim Chan
-
依托单位:
Particulate Characterisation for Pharmaceutical and Engineering Applications
-
批准号:LE0560661
-
项目类别:Linkage Infrastructure, Equipment and Facilities
-
资助金额:$16.36万
-
财政年份:2005
-
负责人:Prof Hak-Kim Chan
-
依托单位:
Synthesis of nanoparticles by impinging liquid-jet precipitation for inhalation drug delivery
-
批准号:DP0451940
-
项目类别:Discovery Projects
-
资助金额:$27.28万
-
财政年份:2004
-
负责人:Prof Hak-Kim Chan
-
依托单位:
Dispersion of Pharmaceutical Powders as Aerosols for Inhalation
-
批准号:DP0208175
-
项目类别:Discovery Projects
-
资助金额:$20.53万
-
财政年份:2002
-
负责人:Prof Hak-Kim Chan
-
依托单位:
国内基金
海外基金
基于电荷泄漏与静电击穿效应的摩擦纳米发电机及电荷转移机制研
究
-
批准号:
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2024
-
负责人:贺文聪
-
依托单位: