Discrete particle simulation of powder dispersion in pharmaceutical aerosol inhalers

药物气雾吸入器中粉末分散的离散颗粒模拟

• 批准号: DP0773755
• 负责人: Prof Hak-Kim Chan
• 金额: $ 20.1万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2007
• 资助国家: 澳大利亚
• 起止时间: 2007-01-17 至 2010-04-15
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0773755
• 关键词: Discrete; particle; simulation; powder; dispersion

A successful completion of the project will i) greatly enhance the Australian R&D profile and capabilities of both computational modelling and pharmaceutical aerosol research in the world; ii) provide an improved delivery of therapeutic dose to patients via inhalers with better performance to enhance the therapeutic benefits; iii) enable wide availability of inexpensive and effective pharmaceutical inhalation products to the Australian community for the treatment of asthma and other diseases, iv) facilitate environmentally friendly technology since powder aerosol delivery does not require any harmful organic solvents to operate.

该项目的成功完成将i）大大提高澳大利亚的研发概况以及世界上计算建模和药物气雾剂研究的能力; ii）通过具有更好性能的吸入器向患者提供更好的治疗剂量，以提高治疗效益; iii）使澳大利亚社区能够广泛获得用于治疗哮喘和其他疾病的廉价和有效的药物吸入产品，iv）促进环境友好技术，因为粉末气溶胶递送不需要任何有害有机溶剂来操作。