Seizure onset detection using tripolar Laplacian electroencephalography

部落学院和大学方案的一个目标是提高为全国土著学生服务的特定高等教育机构的科学、技术、工程和数学教学和研究能力。扩大这些机构的研究能力，扩大了学生在STEM领域追求具有挑战性和回报的职业的机会，为可能与当地相关的领域提供了研究，并鼓励教师社区超越传统课堂寻求智力和专业成长。Dine' College将分析数据集，以验证一种新的基于三极拉普拉斯脑电图（tEEG）的癫痫发作检测方法，该方法使用具有更高灵敏度的自动检测高频振荡（HFO）。与在大型头皮脑电图（EEG）数据集上获得的其他人的最近结果相比，正确检测率（正确检测率）、选择性（每小时的假阳性检测）和检测延迟将构成阳性输出。该项目将有助于通过在Diné学院建立的跨学科工程应用数学（MEA）研究实验室，促进高质量的中学后学生学习和发展，该实验室由PI领导并由本提案资助。四个本科生研究助理职位将在MEA实验室创建，为Diné学院的学生提供宝贵的前沿研究经验。此外，MEA实验室成员和受邀演讲者与实验室合作的讲座和演讲将有助于进一步让学生参与数学和工程学科。

A goal of the Tribal Colleges and Universities Program (TCUP) is to increase the science, technology, engineering and mathematics (STEM) instructional and research capacities of specific institutions of higher education that serve the Nation's indigenous students. Expanding the research capacity at these institutions expands the opportunities for students to pursue challenging, rewarding careers in STEM fields, provides for research studies in areas that may be locally relevant, and encourages a faculty community to look beyond the traditional classroom for intellectual and professional growth. This project aligns directly with that goal, and moreover will increase the body of knowledge on the efficacy of novel devices that may improve the detection of seizure onset.Dine' College will analyze datasets in order to validate a novel tripolar Laplacian electroencephalogram (tEEG) based seizure onset detection methodology using automatically detected high-frequency oscillations (HFOs) with better sensitivity (correct detection rate), selectivity (false positive detections per hour), and detection delay compared to the recent results of others obtained on large scalp encephalogram (EEG) datasets will constitute a positive output. This project will contribute to advancing quality postsecondary student learning and development through the inter-disciplinary Mathematics for Engineering Applications (MEA) research laboratory to be established at Diné College led by the PI of and funded by this proposal. Four undergraduate research assistant positions will be created in the MEA lab providing Diné College students with valuable cutting edge research experience. Moreover, talks and presentations by the MEA lab members and invited speakers collaborating with the lab will help further involve students into mathematics and engineering disciplines.