MRI: Acquisition of a High-Speed Particle Image Velocimetry Instrument

该合同将用于在圣何塞州立大学购买用于进行最先进的流体成像的高速粒子图像测速(PIV)系统。高速PIV是一种利用激光和高帧频摄像机相结合的先进技术来绘制流场图。该系统包括用于测量三维速度分量的立体PIV和用于成像两相微流体系的双色微尺度PIV。这种先进的仪器将促进对广泛的关键应用的创新研究，包括生物医学设备、生化分析和可持续加热、通风和空调技术。此外，PIV系统将被整合到本科生和研究生的教育活动和学生项目中，以加强学生在微流体学和计算流体力学课程中的实践学习。与校园和其他地区组织中感兴趣的研究人员共享PIV系统将促进科学合作。高速PIV系统将使生物流体力学、湍流和微流体学方面的高影响力实验研究成为可能。拟议文书促成的研究项目的例子如下。(1)研究新型三叶式机械瓣的血流动力学性能，为改进下一代人工主动脉瓣的设计奠定基础。(2)自然通风中的湍流及自然风湍流对建筑物内空气交换率的影响研究。(3)支架血栓形成的研究，以了解支架支架附近的壁切应力与血栓形成的关系。(4)用双色微尺度PIV研究狭窄流道内微滴的稳定性。(5)研究颗粒在多孔介质中的运动规律，为电墨水技术的发展奠定基础。这些研究项目的成功将取决于能否获得拟议的高速PIV系统。

This award will be used to acquire a high-speed particle image velocimetry (PIV) system for conducting state-of-the-art fluid imaging at San Jose State University. High-speed PIV is an advanced technique that uses a combination of laser light and cameras with high frame rate to map the flow field. The system includes stereoscopic PIV for measuring three-dimensional velocity components and two-color microscale PIV for imaging two-phase microfluidic systems. This advanced instrumentation will facilitate innovative research on wide-ranging critical applications, including biomedical devices, biochemical analysis, and sustainable heating, ventilation and air conditioning technologies. In addition, the PIV system will be integrated into educational activities and student projects at both undergraduate and graduate levels to enhance hands-on student learning in microfluidics and computational fluid dynamics courses. Sharing the PIV system with interested researchers on campus and other regional organizations will foster scientific collaboration.The high-speed PIV system will enable high-impact experimental research in biofluid mechanics, turbulence and microfluidics. Examples of research projects enabled by the proposed instrument are as follows. (1) Investigation of the hemodynamic performance of novel trileaflet mechanical aortic valves for improving the design of next-generation prosthetic aortic valves. (2) Study on turbulence in natural ventilation and effects of naturally-occurring wind turbulence on the exchange rate of air in buildings. (3) Study on stent thrombosis to understand the relationship between wall shear stress near stent struts and thrombus formation. (4) Investigation of micro-droplet stability in constricted channels using two-color microscale PIV. (5) Study of particle mobility through porous media for the development of electrophoretic ink technology. The success of these research projects will rely on the acquisition of the proposed high-speed PIV system.