CONFERENCE: 2018 Intrinsically Disordered Proteins Gordon Research Seminar

2018年戈登研究研讨会（GRS）在2018年6月30日至7月1日在瑞士Les Diablerets举行。 一系列一年两次的会议中的第三次，2018年IDP GRS，主要由研究生和博士后参加，将汇集来自广泛学科的学员，探索与细胞组织背景下的国内流离失所者研究相关的杰出生物，生物物理和技术挑战。 GRS为促进国际和跨学科合作提供了理想的环境。它还将提供关键的网络机会，以及允许讨论和比较一系列不同的观点-这是如此广泛和多样化的领域的一个关键方面。2018年IDP GRS专注于了解内在无序蛋白质和蛋白质区域（IDP）如何以及为什么可以介导细胞功能。 该计划将包括十个口头报告，伴随着非正式和正式的讨论，以及两个海报会议，所有参与者都希望参加。会议将有少量与会者（最多60名与会者）。演讲将分为四个部分。第一次会议（IDP和大分子组装）将致力于了解IDP的紧急功能，包括它们驱动无膜细胞器形成的能力。第二部分（IDP细胞功能和调节的多样性）将集中在IDP如何介导分子间的相互作用。第三部分（IDP功能的序列决定因素）将考虑氨基酸序列和IDP在体外和体内的行为之间的基本关系。最后一次会议将是一个导师和职业小组，由来自一系列机构类型的教师组成。 除了这个正式的职业小组，我们还有几位来自行业的教师导师和个人，他们将出席会议，以进一步加强职业规划方面的会议。这个奖项反映了NSF的法定使命，并被认为是值得通过使用基金会的智力价值和更广泛的影响审查标准进行评估的支持。

The 2018 Gordon Research Seminar (GRS) on Intrinsically Disordered Proteins (IDPs) in Les Diablerets, Switzerland on June 30 to July 1, 2018. The third of a series of biannual conferences, the 2018 IDP GRS, which is primarily attended by graduate students and postdocs, will bring together trainees from a wide range of disciplines to explore the outstanding biological, biophysical, and technological challenges associated with the study of IDPs in the context of cellular organization. The GRS provides an ideal setting to facilitate international and interdisciplinary collaboration. It will also provide key networking opportunities, as well as allowing a range of different perspectives to be discussed and compared - a key aspect for such a broad and diverse field.The 2018 IDP GRS is focused on understanding how and why intrinsically disordered proteins and protein regions (IDPs) can mediate cellular function. The program will feature ten oral presentations accompanied by informal and formal discussions, as well as two poster sessions in which all participants are expected to participate. The meeting will feature a small number of attendees (up to 60 participants). The presentations will be divided into four sessions. The first session (IDPs and Macromolecular Assemblies) will be devoted to understanding emergent function of IDPs, including their ability to drive the formation of membrane-less organelles. The second session (Diversity of IDP Cellular Function and Regulation) will focus on how IDPs can mediate intermolecular interaction. The third (Sequence Determinants of IDP Function) will consider the fundamental relationship between amino acid sequence and an IDP's behavior in vitro and in vivo. The final session will be a mentorship and career panel featuring faculty from a range of institution types. In addition to this formal career panel, we have several additional faculty mentors and individuals from industry, who will be in attendance to further enhance the career planning aspects of the meeting.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.