RoL:FELS: Symposium: Mitonuclear compatibility as a rule for complex life; January 5, 2019; Tampa, FL

进化生物学导致了农业和医学的突破，并为了解地球的生物多样性提供了一个框架。现代进化生物学的基础是在发现细胞核外的线粒体中有重要的基因之前建立的。这个研讨会被列入《生命法则》，因为它探讨了携带两组不同基因的重要性；这一观点重构了进化生物学的关键理论。关于线粒体基因在生物进化中的作用的新观点需要讨论和进一步发展。为了解决社区中这些发展中的兴趣，2019年综合与比较生物学学会（SICB）会议组织了一个关于生物学的研讨会。研讨会的题目是“超越发电站：整合有丝核进化，生理学和理论在比较生物学”，并将汇集科学家谁是在不同的生物系统的工作，以解决在有丝核生态学新兴主题。演讲者将正式介绍在美国和世界各地的实验室进行的工作。这次会议产生的想法可能会促进医学和农业的发展。本次研讨会将包括从研究生到正教授的不同职业阶段的研究人员，所有演讲者将在综合与比较生物学的特刊上传播这些发现。真核生物是一个古老的共生的结果，因此，真核细胞同时拥有核和线粒体（mt）基因组。线粒体和核基因组之间的相互作用，即有丝核相互作用，是真核生物生物学的固有特征。毫不奇怪，有丝核相互作用被认为是生物体复杂性进化、环境适应、生活史特征进化和物种形成过程的基础。总的来说，在有丝核相互作用的基础上重新思考这种经典的生态进化过程最近被称为“有丝核生态学”。为了解决社区中这些发展中的兴趣，2019年综合与比较生物学学会（SICB）会议组织了一个关于核生态学的研讨会。主讲人包括分子进化、有丝核共适应和冲突理论以及线粒体生理学方面的专家。通过展示这种专业知识的组合，目标是告知社区有丝核相互作用的重要性，鼓励其他人在他们自己的工作中考虑这些类型的相互作用，并开发新的领域（例如，有丝核生态生理学）。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

Evolutionary biology has led to breakthroughs in agriculture and medicine and provides a framework for understanding the Earth's biodiversity. The foundations of modern evolutionary biology were established before the discovery that there are important genes outside of the nucleus of the cell in mitochondria. This workshop is included under Rules of Life as it explores the significance of having genes carried in two distinct sets; this idea reframes key theories in evolutionary biology. New ideas on the role of mitochondrial genes in the evolution of organisms need to be discussed and further developed. To address these developing interests in the community, a symposium on has been organized for the 2019 meeting of the Society of Integrative and Comparative Biology (SICB). The symposium is titled "Beyond the powerhouse: integrating mitonuclear evolution, physiology, and theory in comparative biology" and will bring together scientists who are working in diverse organismal systems to address emerging topics in mitonuclear ecology. The speakers will make formal presentation of the work being conducted in laboratories in the United States and around the world. The ideas that emerge from this meeting may advance medicine and agriculture. This symposium will include a diverse range of researchers that span career stages from graduate student to full professor, and all speakers will disseminate these findings in a special issue of Integrative and Comparative Biology.Eukaryotes are the outcome of an ancient symbiosis and as such, eukaryotic cells possess both a nuclear and mitochondrial (mt) genome. Interactions between the mitochondrial and nuclear genomes, mitonuclear interactions, are an inherent feature of eukaryotic biology. Not surprisingly, mitonuclear interactions have been suggested to underlie the evolution of organismal complexity, environmental adaptation, the evolution of life history traits, and the process of speciation. Collectively, rethinking such classic eco-evolutionary processes in the light of mitonuclear interactions has recently been dubbed "mitonuclear ecology". To address these developing interests in the community, a symposium on mitonuclear ecology has been organized for the 2019 meeting of the Society of Integrative and Comparative Biology (SICB). The speakers include experts in molecular evolution, the theory of mitonuclear coadaptation and conflict, and mitochondrial physiology. By presenting this combination of expertise, the goal is to inform the community of the importance of mitonuclear interactions, encourage others to consider these types of interactions in their own work, and develop new fields (e.g., mitonuclear ecophysiology).This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.