MRI: Acquisition of an Illumina NextSeq 550 System to Support Genomic Research and Research Training at University of Nebraska at Omaha

内布拉斯加大学奥马哈分校（UNO）获得了一项奖励，以获得Illumina下一代测序（NGS）系统，以改善其研究基础设施。UNO是一个新兴的博士/研究机构，并致力于支持该NGS系统的收购和随后建立基因组学设施。利用由训练有素的技术人员组成的内部机器将大大节省成本，并最终提高整个校园，奥马哈地区内外的设施利用率。该设施将以讲习班、学习单元和年度专题讨论会的形式向联合国办事处研究人员和外部用户提供仪器使用方面的培训。来自代表性不足群体的学生的研究和职业机会将通过UNO内完善的社区服务计划提供。所要求的仪器将通过将NGS技术应用于广泛的合作和跨学科项目来支持基础研究。来自整个UNO校园以及邻近机构的研究人员将能够利用NGS系统来解决有关1）神经和行为系统，2）保护遗传学和系统学，3）微生物学和分子遗传学，以及4）分子相互作用和基因调控的广泛的基础科学问题。这些研究将有助于更好地了解基因组如何在细胞或生物体水平上调节复杂的生命系统，并可能在生物多样性和细胞功能等领域产生新的发现。收购Illumina系统将大大推进一系列涉及高通量测序的前沿研究项目，并大大加强大学？该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

An award is made to the University of Nebraska at Omaha (UNO) to acquire an Illumina next-generation sequencing (NGS) system in order to improve its research infrastructure. UNO is an emerging doctoral/research institution and is committed to supporting the acquisition of this NGS system and the subsequent establishment of a genomics facility. Utilizing an internal machine that is staffed by a trained technician will allow significant cost savings and ultimately increased utilization of the facility across the campus, within the Omaha area and beyond. The facility will provide training on instrument usage to UNO researchers and external users in the form of workshops, learning modules, and annual symposia. The research and career opportunities to students from underrepresented groups will be offered through well-established, community-serving programs within UNO. The requested instrumentation will support basic research through the application of NGS technology to a broad spectrum of collaborative and interdisciplinary projects. Researchers from across the UNO campus, as well as neighboring institutions, will be able to utilize the NGS system to address a wide range of fundamental scientific questions regarding 1) neural and behavioral systems, 2) conservation genetics and systematics, 3) microbiology and molecular genetics, and 4) molecular interaction and gene regulation. These studies will lead to a better understanding of how genomes regulate complex living systems at cellular or organismal levels and will likely result in new discoveries in areas such as biodiversity and cellular function. The acquisition of the Illumina system will significantly advance a broad array of leading-edge research projects involving high-throughput sequencing and greatly strengthen the university?s research training capacities in genomics and bioinformatics.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.