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MRI: Acquisition of a Benchtop NMR Instrument with Pulsed Field Gradient and Autosampler for Research and Research Training

MRI: Acquisition of a Benchtop NMR Instrument with Pulsed Field Gradient and Autosampler for Research and Research Training
MRI:购买具有脉冲场梯度和自动进样器的台式 NMR 仪器,用于研究和研究培训
批准号:
2117125
负责人:
Corin Slown
金额:
$14.52万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2021
资助国家:
美国
项目状态:
已结题
起止时间:
2021-08-01 至 2024-07-31

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中文摘要
翻译
该奖项由主要研究仪器、化学研究仪器、生命过程化学和化学结构、动力学和机制B计划支持。位于蒙特利湾的加州州立大学正在购买一台43 MHz台式核磁共振(核磁共振)光谱仪,该光谱仪能够执行常规分析和更复杂的实验,并有助于阐明化合物的分子结构。该仪器支持加州州立大学蒙特利湾分校的约翰·戈尔茨教授及其同事科林·斯隆和艾米·丹诺维茨的研究。该光谱仪允许在各种领域进行研究,如电池材料的开发,探索与小分子相互作用的群体感应途径,以及开展蛋白质-配体结合事件的研究培训。总体而言,核磁共振波谱是化学家可用于阐明分子结构的最强大的工具之一。它被用来识别未知物质,表征分子中原子的特定排列,并研究分子在溶液或固体中相互作用的动力学。对于正在进行前沿研究的化学家来说,获得最先进的核磁共振光谱仪是必不可少的。该仪器是本科生科学教学和科研培训的重要组成部分。授予核磁共振波谱仪的目的是加强各级的研究和教育。它将在为来自代表不足的群体的学生、第一代大学生和这个拉美裔服务机构的女学生提供关键的动手研究经验方面发挥特别大的影响。该奖项反映了NSF的法定使命,并通过使用基金会的智力优势和更广泛的影响审查标准进行评估,被认为值得支持。
英文摘要
This award is supported by the Major Research Instrumentation, Chemistry Research Instrumentation, Chemistry of Life Processes and Chemical Structure, Dynamics and Mechanisms B programs. California State University at Monterey Bay is acquiring a 43 MHz benchtop nuclear magnetic resonance (NMR) spectrometer that has the capabilities to perform both routine analysis and more complex experiments and helps elucidate molecular structures of chemical compounds. The instrument supports the research of Professor John Goeltz and colleagues Corin Slown and Amy Danowitz at California State University at Monterey Bay. This spectrometer allows research in a variety of fields such as development of battery materials, exploring quorum sensing pathways in interactions with small molecules, and carrying out research training in protein-ligand binding events. In general, NMR spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structures of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. This instrument is an integral part of teaching as well as research and research training of undergraduate students in the sciences.The award of the NMR spectrometer is aimed at enhancing research and education at all levels. It will be especially impactful in providing critical hands-on research experience to students from underrepresented groups, first generation college students and female students at this Hispanic Serving Institution.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
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