MRI: Acquisition of a Benchtop X-ray Crystallography System

该奖项由主要研究仪器和化学研究仪器计划支持。来自州立大学犹他州的丽莎·贝罗教授和他的同事孙宇杰和刘天标获得了一台台式单晶X射线衍射仪。一般来说，X射线衍射仪允许准确和精确地测量分子的完整三维结构，包括键距和角度，并提供关于分子相对于相邻分子的空间排列的准确信息。这里描述的研究影响了许多领域，包括有机和无机化学，材料化学和生物化学。该仪器是该机构化学和生物化学研究生和本科生教学和研究及研究培训的组成部分。现代小分子X射线晶体学系统在USU校园的存在对学生来说是变革性的，因为他们目前正在接受这项技术的实践培训，这在收购之前是不可用的。该仪器用于暑期实习计划，使更多的本科生从区域两年制和四年制学校进入USU研究实验室。PI和Co-PI每年夏天都欢迎来自犹他州东南部的美国原住民学生参加为期一周的夏季实验室研究体验，并使用衍射仪。授予这种基本衍射仪的目的是加强各级的研究和教育。它特别影响了影响二价金属/氧促进的脂肪族碳-碳（C-C）键裂解反应的结构和电子因素的研究。该衍射仪允许追求的性质的黄酮醇为基础的一氧化碳释放分子的调查，以及第一行过渡金属配合物与刘易斯酸性金属阳离子在二级配位球的氧化学的研究。该仪器还为研究人员开发用于将二氧化碳还原为甲烷和甲醇的分子电催化剂提供服务，这在经济上具有重要意义。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

This award is supported by the Major Research Instrumentation and the Chemistry Research Instrumentation programs. Professor Lisa Berreau from Utah State University and colleagues Yujie Sun and Tianbiao Liu have acquired a benchtop single crystal X-ray diffractometer. In general, an X-ray diffractometer allows accurate and precise measurements of the full three-dimensional structure of a molecule, including bond distances and angles, and provides accurate information about the spatial arrangement of a molecule relative to neighboring molecules. The studies described here impact many areas, including organic and inorganic chemistry, materials chemistry and biochemistry. This instrument is an integral part of teaching as well as research and research training of graduate and undergraduate students in chemistry and biochemistry at this institution. The presence of a modern small molecule X-ray crystallography system on the USU campus is transformative for students, as they are currently receiving hands-on training in this technique that was unavailable before the acquisition. The instrument is used in summer internship programs that bring additional undergraduates into USU research labs from regional two- and four-year schools. The PI and Co-PIs welcome Native American students from southeast Utah each summer to participate in a weeklong summer research experience in their laboratories and utilize the diffractometer.The award of this basic diffractometer is aimed at enhancing research and education at all levels. It especially impacts studies on structural and electronic factors that influence divalent metal/oxygen-promoted aliphatic carbon-carbon (C-C) bond cleavage reactions. The diffractometer allows the pursue of investigations of the properties of flavonol-based carbon monoxide-releasing molecules as well as studies of oxygen chemistry of first row transition metal complexes with a Lewis acidic metal cation in the secondary coordination sphere. The instrumentation also serves investigators developing molecular electrocatalysts for carbon dioxide reduction to methane and methanol which is economically important.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.