CRIF:MU Acquisition of a Benchtop Electrospray Ionization Time of Flight Mass Spectrometer

CRIF:MU 购置台式电喷雾电离飞行时间质谱仪

• 批准号: 0946858
• 负责人: Vaidhyanathan Ramamurthy
• 金额: $ 30.88万
• 依托单位: University of Miami
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0946858&HistoricalAwards=false
• 关键词: CRIF; MU; Acquisition; Benchtop; Electrospray

With this award from the Chemistry Research Instrumentation and Facilities: Departmental Multi-User Instrumentation program (CRIF:MU), Professor V. Ramamurthy and colleagues Burjor Captain, Angel E. Kaifer, Francisco M. Raymo and Norito Takenaka of the University of Miami will acquire a liquid chromatography electrospray ionization mass spectrometer. Research activities that will be facilitated by the new instrumentation include investigations of supramolecular photochemistry and electrochemistry, studies of molecular self-assembly, elucidation of protein signaling pathways, development of helical chiral asymmetric catalysts, synthesis of hydrogen-storing metal clusters and investigations of luminescent switches for fluorescent spectroscopy.In a liquid chromatograph interfaced mass spectrometer, the chromatograph separates a mixture into its molecular components. These flow into the mass spectrometer where they are ionized by an electrospray technique. The mass spectrometer measures the molecular mass of each component and its fragments. This facilitates determination of the structure of the constituents of the mixture. The electrospray ionization technique allows large nonvolatile molecules such as proteins and supramolecular clusters to be analyzed directly from the liquid phase. This acquisition will benefit undergraduate and graduate students through research programs in the department and will allow the introduction of this modern analytical technique into undergraduate chemistry laboratories.

凭借化学研究仪器和设施：部门多用户仪器计划（CRIF：MU）的这一奖项，V. Ramamurthy教授及其同事Burjor Captain，Angel E。作者：弗朗西斯科M.迈阿密大学的Raymo和Norito Takenaka将获得液相色谱电喷雾电离质谱仪。 新仪器将促进研究活动，包括超分子光化学和电化学的研究，分子自组装的研究，蛋白质信号通路的阐明，螺旋手性不对称催化剂的开发，储氢金属簇的合成和荧光光谱学发光开关的研究。色谱仪将混合物分离成其分子组分。 它们流入质谱仪，在那里它们被电喷雾技术电离。 质谱仪测量每个组分及其碎片的分子量。这有助于确定混合物组分的结构。 电喷雾离子化技术允许直接从液相分析大的非挥发性分子，如蛋白质和超分子簇。此次收购将有利于本科生和研究生通过在部门的研究计划，并将允许这种现代分析技术引入本科化学实验室。