Triboelectric Nanogenerator Ion Mobility-Mass Spectrometry for Studying Cultural Heritage Materials

Daniel Vallejo被授予2021财年数学和物理科学提升博士后研究（NSF mp - ascend）奖学金，以开展一项与扩大乔治亚理工学院化学领域代表性不足的群体参与相关的研究和活动。该项目由Daniel Vallejo执行，名为“摩擦纳米发电机离子迁移-质谱法研究文化遗产材料”。将在指导科学家Facundo M. Fernández的指导下进行。该项目得到数学和物理科学理事会多学科活动办公室的支持。该研究项目探讨了一种基于摩擦电纳米发电机（TENG）离子源与离子迁移-质谱（IM-MS）耦合的文化遗产材料化学成分分析新方法。与传统的质量选择分析方法相比，该方法最大限度地减少了样品消耗，同时还区分了油漆和其他文化遗产材料中蛋白质结合剂的结构差异，而这些差异无法单独使用质谱法进行鉴定。该研究计划包括系统地表征模拟样品中的蛋白质结构和稳定性，以及开发一个新的数据库，用于汇编与该社区相关的数据。该项目的更广泛影响包括文化遗产材料的重要性，以及通过吸引来自不同背景的学生，研究这些材料将扩大STEM研究参与的可能性。该项目支持的活动还将科学家和保护人员聚集在科学和文化遗产研究的交叉点上。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

Daniel Vallejo is awarded a FY21 Mathematical and Physical Sciences Ascending Postdoctoral Research (NSF MPS-Ascend) Fellowship to conduct a program of research and activities related to broadening participation by groups underrepresented in Chemistry at Georgia Tech. The project being performed by Daniel Vallejo, entitled Triboelectric Nanogenerator Ion Mobility-Mass Spectrometry for Studying Cultural Heritage Materials, is to be conducted under the guidance of mentoring scientist Facundo M. Fernández. This project is supported by the Office of Multidisciplinary Activities in the Mathematical and Physical Sciences Directorate.The research project examines a new approach for analyzing the chemical constituents of cultural heritage materials based on the coupling of a triboelectric nanogenerator (TENG) ion source with ion mobility-mass spectrometry (IM-MS). The approach minimizes sample consumption compared with traditional mass-selective methods of analysis, while also distinguishing structural differences of protein binding agents in paints and other cultural heritage materials that could not be identified using mass spectrometry alone. The research plan includes a systematic characterization of protein structure and stability in simulated samples, as well as development of a new database for compiling data that are relevant to the community. The broader impacts of the project include the importance of cultural heritage materials and the likelihood that studying these materials will broaden participation in STEM research by engaging students from diverse backgrounds. Activities supported by this project also bring together scientists and conservators at the intersection of science and cultural heritage research.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.