Mimicking peptide structure - towards an aqueous environment

在本提案中，我们发展了对“弱”和“强”力之间平衡的基本理解，以定义肽和蛋白质的性质。这将允许设计具有定制化学和物理特性的新生物探针和材料，用于生物工程，生物技术，蛋白质组学和药物设计。其中一个例子是设计和制备一种新的化学制剂，用于白内障的非手术治疗，白内障是全世界失明的主要原因。

In this proposal we develop a fundamental understanding of the balance between 'weak' and 'strong' forces to define the properties of peptides and proteins. This will allow the design of new biological probes and materials with tailor-made chemical and physical properties for use in bioengineering, biotechnology, proteomics, and drug design. One such example is the design and preparation of a new chemical agent for the non-surgical treatment for cataract, the major cause of blindness world-wide.