Molecular Investigations into Polyglutamine Repeat Proteins
Molecular Investigations into Polyglutamine Repeat Proteins
批准号:
DP0773627
负责人:
Prof Stephen Bottomley
金额:
$20.8万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2007
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2007-01-02 至 2009-12-31
中文摘要
拟议的研究计划将为控制蛋白质聚集和疾病的过程提供重要的基础见解。研究蛋白质聚集的核心过程是很重要的,因为它将进一步加深我们对这些至关重要的事件和我们对疾病过程的理解。这些知识将提高澳大利亚的国际研究地位,并有可能产生防止神经变性的新疗法。
英文摘要
The proposed research program, will provide significant fundamental insight into the processes that control protein aggregation and disease. Investigating processes central to protein aggregation is important, as it will further our understanding of these critically-important events and our understanding of disease processes. Such knowledge will increase Australia's international research standing, as well as having the potential to generate novel therapies, that prevent neurodegeneration.
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会议论文
Analysing the detrimental effects of polyglutamine expansion
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批准号:DP1095102
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项目类别:Discovery Projects
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资助金额:$20.89万
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财政年份:2010
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负责人:Prof Stephen Bottomley
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依托单位:
Uncoupled Research Fellowship
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批准号:nhmrc : 436670
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项目类别:Research Fellowships
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资助金额:$53.21万
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财政年份:2007
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负责人:Prof Stephen Bottomley
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依托单位:
Modulation of protein folding pathways: a new platform technology for molecular medicine.
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批准号:LP0347910
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项目类别:Linkage Projects
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资助金额:$15.71万
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财政年份:2003
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负责人:Prof Stephen Bottomley
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依托单位:
The Structure Function and Biology of Serpins
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批准号:DP0342866
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项目类别:Discovery Projects
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资助金额:$31.41万
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财政年份:2003
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负责人:Prof Stephen Bottomley
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依托单位:
The molecular analysis of Conformational Disease
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批准号:nhmrc : 194457
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项目类别:Career Development Fellowships
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资助金额:$28.34万
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财政年份:2002
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负责人:Prof Stephen Bottomley
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依托单位:
Molecular analysis of alpha-1-Antitrypsin misfolding: a cause of alpha-1-antitrypsin deficiency
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批准号:nhmrc : 124493
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项目类别:NHMRC Project Grants
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资助金额:$17.06万
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财政年份:2000
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负责人:Prof Stephen Bottomley
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依托单位:
海外基金