Epigenesis and sociality: Unraveling the link between nutrition and the genome - how do genes and environment interact to produce phenotypes?

这个项目有能力改变我们对基因和环境如何相互作用以产生整个生物体表型的理解。它将提供关于整个基因组如何对营养作出反应以及外部因素如何强制共同可遗传基因程序的差异表达的新数据。该项目的国家和社区利益将是保持澳大利亚在复杂自组织系统的表观遗传学和高级遗传学方面的领导地位。该项目的研究结果有可能适用于解释饮食引起的人类基因表达变化的调控网络。

This project has the capacity to transform our understanding of how genes and environment interact to produce whole-organism phenotypes. It will provide novel data on how an entire genome responds to nutrition and how external factors can enforce a differential expression of a common heritable genetic program. The national and community benefits of the project will be to maintain Australian leadership in epigenetics and advanced genetics of complex self-organizing systems. The findings of this project have the potential to be applicable to explaining regulatory networks underlying diet induced changes in human gene expression.