The relationship between oral health and the development of malnutrition in older adults – secondary data analyses of the Longitudinal Aging Study Amsterdam (LASA)

老年人营养不良是导致不良临床结果和增加保健费用的常见问题。随着老年人人口群体的增长，老年人营养不良已成为一个重要的公共卫生问题。营养不良的起因是多方面的，可能受到与健康有关、心理或社会经济因素的影响。一个潜在的可改变的危险因素是口腔健康状况。研究表明，口腔因素与营养不良之间存在关联。然而，大多数研究是横断面的，主要调查口腔功能的单一方面，大多数是在机构环境中进行的，通常在亚洲和其他新兴国家进行，限制了对欧洲情况的可转移性。因此，本项目的目的是(a)调查在社区居住的老年人9年后不同口腔健康状况指标与营养不良事件之间的关系，(b)分析随访期间口腔健康状况变化与营养状况之间的关系。阿姆斯特丹纵向老龄化研究（LASA）是一项基于人群的纵向试验，采用了充分的抽样程序，使样本具有荷兰老年人的代表性。本项目将使用2007年LASA生活方式研究（n=1,054）和2015/16年LASA浪潮的数据，因为这些调查包括口腔健康状况和营养状况的综合信息。为了回答研究问题，将使用多元统计方法进行二次数据分析。

Malnutrition in older adults is a common problem leading to negative clinical outcomes and increased health care costs. As the population group of older adults is growing, malnutrition in older adults becomes an important public health issue. The origin of malnutrition is multifactorial and can be influenced by health-related, psychological or socio-economic factors. One potentially modifiable risk factor is the oral health status. Research has shown an association between oral factors and malnutrition. However, most of the studies were cross-sectional, investigated mainly single aspects of oral function, were mostly performed in institutional settings, and were often conducted in Asia and other emerging countries, limiting the transferability to the situation in Europe. Therefore, the aims of this project are (a) to investigate the relationship between different measures of oral health status and incident malnutrition after nine years in community-dwelling older adults and (b) to analyze the association between changes in oral health and nutritional status over the follow-up period. The Longitudinal Aging Study Amsterdam (LASA) is a population-based longitudinal trial that applied adequate sampling procedures making the sample representative for older adults living in the Netherlands. For this project the data of the LASA Lifestyle Study in 2007 (n=1,054) and the LASA wave of 2015/16 will be used as these investigations include comprehensive information on oral health status and nutritional status. To answer the research questions secondary data analyses will be conducted using multivariate statistical approaches.