Study of atomic Ne penning laser for photodynamic therapy of cancer

本文从实验和理论两方面研究了原子氖笔激光光动力治疗癌症的效果。结果表明：(1)利用自行研制的霓虹灯笔划激光码，明确了实现高能量输出和高效率的操作条件。(2)最佳气体配比为Ne/H_2=16/40 Torr，最佳抽气速率为0.5 MW/cm^3。在此参数下，输出功率密度为4.4 W/cm^3，效率为8.5x10^<-6>。(3)当泵浦速率大于0.5 MW/cm^3时，放电电子对上激光能级的失活作用增大，导致效率降低。(4)稳定放电的实现导致了千瓦级氖激光器的产生。(5)作为氖激光器的书写伙伴，H_2优于D_2。(6)通过输送氖激光脉冲穿过石英光纤，高效抽运HpD。

The atomic neon penning laser for photodynamic therapy of cancer is studied experimentally and theoretically. As a result, the following results are obtained :(1)Using a neon penning laser code developed by us, the operational conditions for achieving high energy output and high efficiency are made clear.(2)It is found that the optimun gas mixture is Ne/H_2=16/40 Torr and the optimum pumping rate is 0.5 MW/cm^3. At this parameter the output power density of 4.4 W/cm^3 is obtained at an efficiency of 8.5x10^<-6>.(3)At higher pump rates than 0.5 MW/cm^3, deactivation of the upper laser level by discharge electron becomes larger, resulting in the decrease of the efficiency.(4)Achievement of the stable discharge leads to the klowatt-class neon laser.(5)As a penning partner of the neon laser, H_2 is better than D_2.(6)By delivering the neon laser pulse through the quarts fiber, HpD is efficiently pumped.