Ecological study of Bacteroides species habored in the intestine of laboratory animals.

从小鼠、大鼠、兔和豚鼠盲肠内容物中分离到1,080株拟杆菌科细菌。除一只正常对照小鼠外，其余小鼠均分离到Untyable-1组。在CF#1小鼠中，普通拟青霉为优势种。从NC小鼠体内分离出不能分型的1、2、3组，而不是“脆弱”组和其他组。在3只BALB/c小鼠中有2只分离到脆弱芽孢杆菌。在大鼠盲肠内容物中未检测到不分型-1群，优势种为巴氏杆菌和脆性巴氏杆菌，其次为蛋黄杆菌和内脏巴氏杆菌。在豚鼠中，巴氏杆菌是优势种，从所有豚鼠中分离到。从3只豚鼠中分别分离到1株均匀芽孢杆菌和1株脆弱芽孢杆菌。与其他动物相比，兔肠道中携带的类杆菌种类较多。仅从兔体内分离到卵形芽孢杆菌、条斑芽孢杆菌、微小纤毛虫。兔的优势种为巴氏杆菌、均匀巴氏杆菌和脆性巴氏杆菌，优势种为卵形巴氏杆菌和蛋黄杆菌。小鼠和大鼠分离株在菌群水平上存在一定的差异，在无菌小鼠口服猪粪接种产生的猪菌群中，“脆弱”菌群与正常小鼠相同，未分离到猪肠道优势种猪瘟杆菌。这些数据表明，动物可以选择最适合的类杆菌物种。

Total 1,080 isolates of Bacteroidaceae from cecal contents of mice, rats, rabbits and guineapigs were identified by biochemical tests. Untypable-1 group was isolated at the predominant level from all mice except one of NC mice. IN CF#1 mice, B.vulgatus was dominant species. Untypable 1,2,3 groups but not "fragilis" group and other groups were isolated from NC mice. In two of three BALB/c mice, B.fragilis were isolated. In rat cecal contents, untypable-1 group was not detected and B.vulgatus and B.fragilis were predominant species and B.eggerthii and B.splanchnicus were followed. In guinea-pigs, B.vulgatus were the predominating species and isolated from all guinea-pigs. B.uniformis and B.fragilis were also isolated from one of three guinea-pigs respectively. A lot of species of Bacteroides were harbored in rabbit intestine as compared with other animal species. B.ovatus, B.thetaiotaomicron, Rikennera microfusus were isolated from only rabbits. In rabbits B.vulgatus, B.uniformis and B.fragilis were the predominating species and B.ovatus, B.eggerthii were the dominant. There were some differences on biovor level of B.vulgatus between mouse and rat isolates.In pig-flora-associated mice which were produced by oral inoculation with pig feces to germfree mice, "fragilis" group occupied as same as normal mice and B.suis which was the predominant species in pig intestine were not isolated. These data indicate that animals can select the most suitable Bacteroides species.