Intracellular calcium signaling in malignant brain tumor cells and new application to the management of the brain neoplasms

1. 组织相容性抗原基因和原癌基因表达在小鼠神经母细胞瘤脑内致瘤性中的作用。钙阻滞剂和肿瘤坏死因子α对神经母细胞瘤-胶质瘤杂交细胞膜电位的影响。小鼠恶性胶质瘤细胞系细胞内和细胞间钙信号的分析。多普勒超声与内镜术中监测在立体定向神经外科中的临床意义。单光子发射计算机断层扫描（SPECT）在脑肿瘤术前鉴别中的临床作用。恶性脑肿瘤手术、放疗、化疗及免疫治疗多模式治疗的临床研究。

1. Role of histocompatibility antigen gene and proto-oncogene expressions in intracerebral tumorigenicity of mouse neuroblastoma.2. Effect of calcium blocker and tumor necrosis factor-alpha on the membrane potential of cultured neuroblastoma-glioma hybrid cells.3. Analysis of intra- and intercellular calcium signaling in a mouse malignant glioma cell line.4. Clinical significance of Doppler ultrasound and endoscopic intraoperative monitoring in the stereotactic neurosurgery.5. Clinical role of single photon emission computed tomography (SPECT) in preoperative discrimination of brain neoplasms.6. Clinical investigation of multimodel treatments consisting of surgery, radiotherapy, chemotherapy and immunotherapy for malignant brain neoplasms.