Effect of <Phytic Acid-Stannous Fluoride> Primer on Adhesion

植酸(PYA)-氟化亚锡(SnF_2)&gt；底漆是我科研制的用于牙科树脂粘接剂与牙体基材粘接的牙体处理剂。在本研究中，使用含有功能单体和聚羧酸的各种市售粘固剂，考察了该底漆对粘接树脂和玻璃离子粘固剂与牙基、铸造陶瓷和羟基磷灰石粘接的影响。在所有的粘合系统中，该底物的效果各不相同。此外，还获得了解释该底漆作用机理的新信息，该底漆对牙体基材中不含色原等有机成分的铸造陶瓷和羟基磷灰石具有良好的粘接效果。这一结果表明，PYA与牙齿基质中的无机成分磷灰石之间的化学作用与该底漆对牙齿粘结的影响有关。用对牙齿脱矿非常温和的PYA盐部分替代PYA底漆，效果与原底漆相同。这一结果表明，Sn2+与PYA和含水泥的功能单体或聚羧酸之间的化学作用是该底漆对牙齿基质的主要作用，而不是其对牙齿基质的脱矿能力。用该底物进行处理需要两步，分别用PYA和SNF2溶液。PYA和SNF2混合的一步引发剂的效果低于原两步引发剂。这一结果也支持该引发剂的作用机理。然而，这一假设非常复杂。因此，应通过ESCA、IR光谱等仪器分析手段进行进一步的研究，以证明该引物的作用机理。

The <Phytic acid (PYA)-Stannous Fluoride (SnF_2) > primer has been developed as the tooth conditioner for bonding of dental resin adhesives to tooth substrates in our department. In the present study, the effects of this primer on bonding of adhesive resin and glass ionomer cements to tooth substrates, castable ceramics and hydroxyapatites were examined using various commercial cements containing functional monomers and polycarboxylic acids. In all bonding-systems, this primer was vary effective. In addition, the new informations with which could explain the action mechanism of this primer were got.This primer was effective on bonding to castable ceramics and hydroxyapatites which do not contain organic components such as collargen in tooth substrates. This results suggest that the chemical interaction between PYA and apatites which is an inorganic component of tooth substrates is related to the effects of this primer on bonding to tooth. The primer in which PYA salt partially substituted with sodium, the treatment with which was very mild for demineralization to tooth, was used in place of PYA had the same effects as the original primer. This result suggests that the chemical interaction bwtween Sn^<2+> fixed tooth substrates with PYA and functional monomers or polycarboxylic acids containing cements is the main effect of this primer rather than its demineralization ability to tooth substrates. The treatment with this primer requires two steps with PYA and SnF_2 solutions, respectively. The effect of the one-step primer in which PYA and SnF_2 were mixed was lower than that of the original two-step primer. This result also supports the action mechanism of this primer mentioned above. However, this hypothesis is very complex. Therefore, further reseraches should be performed by means of instrumental analysis such as ESCA and IR specroscopy to prove the action mechanism of this primer.