Metalloproteins and metalloenzymes

生命系统中的大部分化学反应和物理运动都是由蛋白质进行的。从氨基酸产生蛋白质的信息存储在基因中，但许多生物过程依赖于蛋白质组装后添加到蛋白质中的额外原子或分子(辅助因子)。例如，超过30%的蛋白质含有对其功能至关重要的金属原子。我们正在研究这些金属蛋白和金属酶的结构，以便我们能够更好地了解它们的活动，长期目标是为生物技术和/或药物创造新的分子。

Most of the chemical reactions and physical movements in living systems are carried out by proteins. The information for producing proteins from amino acids is stored in the genes, but many biological processes depend on additional atoms or molecules ('cofactors') that are added to a protein after it is assembled. For example, more than 30% of all proteins contain metal atoms which are essential for their function. We are studying the structures of such metalloproteins and metalloenzymes so that we can better understand their activities with long term aims of creating new molecules for biotechnology and/or drugs.