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Behavior-genetical. physio-biochemical. and ecological study on the genesis of individual differences in behavior.

Behavior-genetical. physio-biochemical. and ecological study on the genesis of individual differences in behavior.
行为遗传。
批准号:
61450010
负责人:
FUJITA Osamu
金额:
$3.2万
依托单位国家:
日本
项目类别:
Grant-in-Aid for General Scientific Research (B)
财政年份:
1986
资助国家:
日本
项目状态:
已结题
起止时间:
1986 至 1988

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中文摘要
翻译
本研究的目的是确定个体行为差异产生的原因和过程。Behavior-genetical。Physio-biochemical。并利用筑波大学选取的高、低情绪反应大鼠两种近交系进行了这些问题的生态学研究。对筑波情绪品系(THE和TLE)及其衍生的4个杂种(F1、F2、B1、B2)进行了跑道情绪测试。从移动得到的结果数据。排便和其他行为测量采用孟德尔交叉分析。在所有行为测量中均检测到加性效应。在男性中发现了对较少情绪的定向支配,而在女性中则没有。三种表现情绪的行为指标之间存在遗传相关性。估计遗传力和相关基因座数。研究了筑波情绪应激是否与选择相关。儿茶酚胺、选择素及其代谢物的脑区含量是否存在差异。2、肾上腺素、去甲肾上腺素、多巴胺、血清素、5-羟基吲哚乙酸、3,4-二羟基苯基乙酸、3-甲氧基tryamine的含量差异显著。筑波情绪品系在有遮蔽的露天场地、有两个端室的直跑道和迷宫中的行为差异显著。在囤积行为、挖掘行为和攻击行为方面,大鼠和小鼠也存在应变差异。对筑波情绪菌株进行了氯化锂注射引起的疾病与氯化钠味道配对的厌味条件作用。两种菌株在一次试验后都获得了味觉厌恶条件反射,并保持了四天。然而,前者消除味觉厌恶的速度比后者快。在跑道、空地上对大鼠和小鼠的行为测量。采用主成分分析法对一个i-maze进行了分析。两种品系在半自然环境中繁殖3年,其种群大小与雄性性行为特征有关。少
英文摘要
The object of this study is to determine the causes and the processes of the genesis of indvivdual differences in behavior. Behavior-genetical. Physio-biochemical. and ecological studies on these problems were performed by using of two inbred strains of rats which had been selected for high and lowemotional reactivity in university of Tsukuba.1. Tsukuba Emotinal Strains (THE and TLE) and their derived four hybrids (F1, F2, B1, B2) were tested for their emotionality in a runway. The resulting data from ambulation. Defecation and other behavioral measures were subjected to the Mendelian cross analysis. Additive effects were detected in all behavioral measures. Directional dominance toward less emotionality was detected in male, wheres in female dominance was absent. Genetic correlations among three behavioral measures which indicated emotionality were found. Heritability and the number of locus related were estimated.2. Tsukuba Emotional Strains were examined whether selection-assoslated … More differences in brain regional contents of catecholamines, seletonin, and their metabolltes exit or not. Two strains significantly differed with regard to adrenaline, noradrenaline, dopamine, seretonin, 5-hydroxyinodoleacetic acid, 3,4-dihydroxyphenylacetic acid, and 3-methoxytryramine.3. Tsukuba Emotinal Strains were significantly different on their behaviors in an openfield with shelter, a straight runway with two end-compartments, and an i-mazy. Strain differences of hoarding behavior, digging behavior, and aggressive behavior were also detected between THE and TLE.4. The taste-aversion conditioning in which taste of NaCl was paired with an illness induced by an injection of lithium chloride was conducted on Tsukuba Emotional Strains. Both strains acquired taste aversion conditioning after one trial, and they retained this for four days. TLE, however, extingwished the taste aversion faster than THE.5. Behavioral measures of rats and mice in a runway, an openfield. and an i-maze were analyzed by the mothod of principal component analysis.6. Population size of both strains bred in a seminatural field for three years would be related to the characteristics of male's sexual behavior. Less
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会议论文
増井誠一郎、牧野順四郎、藤田統: 薬物・神経・行動. 8. 229-230 (1988)
Seiichiro Masui、Junshiro Makino、Osamu Fujita:毒品、神经和行为。8. 229-230 (1988)。
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FUJITA, Osamu: "Genetic determinant of emotinal reactivity in the Runway Test and behavioral differences in the Open-field with Shelter in the Tsukuba Emotional Strains of rats." Tsukuba Psychological Research.10. 53-67 (1988)
FUJITA, Osamu:“跑道测试中情绪反应性的遗传决定因素以及筑波情绪品系大鼠在开放场地和庇护所中的行为差异。”
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増井誠一郎、藤田統: 心理学研究. 60. (1989)
增井诚一郎,藤田修:心理学研究 60。(1989)
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共 16 条
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