Automatic scanner for whole slide imaging

核心设备细胞成像（CFCI）的许多用户必须对整个系列的幻灯片进行成像。使用我们核心设施中现有的显微镜，这是一个非常耗时的过程。通过使用具有标准化程序的自动显微镜来获取数据将更加省时。这可以通过自动载玻片扫描仪来实现，该扫描仪每次运行最多可加载100张载玻片。通过应用单独的用户设置，可以以完全自动化的方式收集数据，从而实现具有高重现性的标准化图像采集。一系列的样本可以在夜间记录，以提高数据收集的效率。这导致用户在成像期间操作显微镜所需的时间大大减少。选择的显微镜应用于分析亮场以及荧光样品。它为我们核心设施的用户提供了广泛的分析。由于这种自动校准，可以获得可重复和一致的数据，用于进一步的定量和分析。

Many users of the Core Facility Cellular Imaging (CFCI) have to image whole series of slides. Using the currently available microscopes in our core facility, this is a very time consuming process. It would be much more time efficient to acquire the data by using an automated microscope with standardized procedures. This can be achieved with an automatic slide scanner that can be loaded with up to 100 slides per single run. Data can be collected in a fully automated way by applying individual user settings, enabling standardized image acquisition with high reproducibility. Series of samples can be recorded over night to increase the efficiency of data collection. This leads to an enormous reduction in time necessary for the users to operate the microscope during imaging. The microscope of choice should be used to analyze both brightfield as well as fluorescent samples. It offers a broad spectrum of analysis to the users of our core facilty. Due to this automatic calibration, reproducible and consistent data can be acquired for further quantifications and analyses.