Development of Tele-Neuroendovascular Therapy Support System

1.利用超级计算机进行脑血管三维重建：该方法是利用超级计算机流体动力学分析，在高分辨率3D-DSA数据采集后的几小时内开发的。现在可以进行四维分析（考虑到心脏周期的三维分析）。应用于临床病例分析：分析脑动脉瘤、动脉粥样硬化、动静脉瘘，对治疗有有益贡献。重点分析了脑动脉瘤的发生、生长和破裂，并提出了一些血流动力学上的重要线索。神经血管内治疗虚拟现实模拟研究进展：利用PHANToM力反馈装置，模拟神经血管内治疗成为可能。原始的导丝操作仿真软件使我们能够使用该虚拟现实系统进行训练，预先模拟真实治疗等。未来发展方向：随着虚拟现实系统的发展及其在训练中的应用，远程神经血管内治疗将成为现实。利用微型机器人技术开发各种类型的主从系统势在必行。本研究成果将广泛应用于以科学证据为基础的脑血管疾病病理生理细致分析。

1.Three-dimensional reconstruction of brain vessels using super-computer: The method was developed using super-computer fluid dynamics analysis within few hours from data acquisition by high resolution 3D-DSA. Four dimensional analysis is now possible (3D with cardiac cycle into account).2.Application into clinical case analysis: Brain aneurysm, atherosclerosis and arterio-venous fistulas were analyzed with useful contribution for the treatment. Special attention was paid to analyze the initiation, growth and rupture of brain aneurysm and some hemodynamically significant clue was brought in.3.Development of virtual reality simulation of neuroendovascular therapy: Using PHANToM force-feed back device, it is now possible to simulate neuroendovascular therapy. Primitive guide wire mainipulation simulation software enabled us to use this virtual reality system for training, simulation beforehand the real treatment and so on.4.Future directions: Tele-Neuroendovascular therapy will be a reality with the development of virtual reality system and its application into training. It is mandatory to develop various types of master-slave system utilizing micro-robotics technology. The results of this research will be widely applied to the scientific evidence based pathophysilogical meticulous analysis of cerebrovascular diseases.