STUDY OF POLYMER-SUPPORTED DESS-MARTIN HYPERVALENT IODINE REAGENT

在克里思（cat.）存在下，以聚[4-（二乙酰氧基碘）苯乙烯]（PSDIB）为氧化剂，在室温下成功地将伯醇和仲醇氧化为相应的醛和酮。在丙酮中，作为一种环境友好的方法。在这里，聚合物负载的hypervapent碘定量回收通过简单的过滤从反应混合物中，和PSDIB再生处理与过氧乙酸和重复使用成功。以前的方法如Swern氧化和Dess-Martin氧化可以被本发明的方法取代，因为本发明的将伯醇和仲醇分别氧化成相应的醛和酮的方法作为操作简单和环境友好的方法是有效和安全的，并且可以用于药物和农业化学物质的合成

Primary and secondary alcohols were successfully oxidized to the corresponding aldehydes and ketones at room temperature in good yields, respectively, with poly[4-(diacetoxyiodo)styrene] (PSDIB) in the presence of TEMPO (cat.) in acetone, as an environmentally friendly method. Here, polymer-supported hypervapent iodine was quantitatively recovered by simple filtration from the reaction mixture, and PSDIB was regenerated by treatment with peracetic acid and reused successfully. The previous methods such as Swern oxidation and Dess-Martin oxidation may be substituted by the present method, since the present oxidation of primary and secondary alcohols to the corresponding aldehydes and ketones, respectively, is effective and secure as an operationally simple and environmentally benign method, and can be used for the synthesis of pharmaceutical and agrochemical substances