Research on circadian variations of biological variables, such as blood pressure, body temperature, etc. in different sleep-wake patterns III.

为了研究生物变量的昼夜变化，当睡眠时相改变时，14名学生（10名男性，4名女性）在2003年在受控的物理条件和生活环境下连续研究了72小时。睡眠时间分别为第1天00：00 ~ 07：00、第2天0、第3天12：00 ~ 19：00。我们也曾报道过，不同的变量和不同的受试者会以不同的速度调整昼夜节律变化以适应不同的睡眠-觉醒时间表，而这次我们研究的是女性。变量的昼夜变化在两性中表现出几乎相同的模式，但不同的中介。然而，在某些变量中，女性表现出比男性更高的振幅。尿褪黑激素分泌，我们第一次研究，转移睡眠后缓慢转移。对相位变化的反应也取决于人。我们调查了大学生在春夏季的日常生活时间。我们报告说，在假日，他们比工作日醒来晚，那些不吃早餐的人比吃早餐的人醒来晚得多。这次我们在冬季进行了调查。他们的日常生活的时间并没有改变季节之间，但是，在女性的时间是不同的男性，主要是由于吃早餐。

To investigate the changes revealed in circadian variations of biological variables, when a sleep phase was shifted, fourteen students (ten males, four females) were studied for 72 hours continuously under a controlled physical conditions and living environment in 2003. Sleep hours were from 00:00 to 07:00 on the 1st day, zero on the 2nd day, and from 12:00 to 19:00 on the 3rd day.We had studied blood pressure, pulse rate, and biochemical and endocrinological variables in blood and urine in males. And we had reported that adjustment of circadian variations to changed sleep-wake schedules occurred at different rates by variable and also by subject.This time we studied females together. Circadian variations of variables showed almost same patterns in both genders, with different mesors. However, in some variables females showed higher amplitudes than in males.Urinary melatonin excretion, that we studied for the first time, shifted slowly after the shifted sleep. The reactions to the phase shift also depended on persons.We had surveyed timings of daily life in university students during Spring to Summer seasons. And we reported that on holidays they woke up later than on weekdays, and that those who did not eat breakfast woke up much more later than those who had breakfast. This time we conducted surveys during Winter. Their timings of daily life did not change between seasons, however, timings in females were different to males, mainly, due to eating of breakfast.