Aprospective study of the effects of cancer-prone personalities on the prognosis of lung cancer patients

目的：探讨Grossarth-Maticek提出的“1型”(无望、情绪抑制、癌症易患)、“4型”(自主型、健康型)和“5型”(理性/反情绪型、易患癌症)人格特征对肺癌患者预后的预测价值。方法：对68例肺癌患者按1、4、和5个人格问卷，直到死亡或在入院后最长5.7年被审查。结果：类型1分高或类型4分低的患者的诊断阶段倾向于更高。单变量COX比例风险模型显示，倾向于1型或5型的高风险与死亡风险的增加有关。然而，对年龄、表现状态和阶段的调整减弱了与1型的关系，只留下5型作为显著相关的人格因素。结论：5型倾向高可能预示肺癌患者的生存不良，而1型和4型可能不是独立的预测因素。

Objective : To examine predictive values for the effect of the "Type 1"(hopeless and emotion-suppressive, cancer prone), "Type 4"(autonomous, healthy), and "Type 5"(rational/antiemotional, cancer prone) personalities proposed by Grossarth-Maticek on the prognosis of lung cancer patients.Methods : 68 lung cancer patients were scored on the Types 1,4, and 5 personality scales of the Short Interpersonal Reactions Inventory and were followed until the date of death or were censored at a maximum of 5.7 years after entry.Results : The stage at diagnosis tended to be higher in patients with a high Type 1 or a low Type 4 score. A univariate Cox proportional hazards model showed that a high tendency toward Type 1 or Type 5 was related to an increased hazard of death. Adjustment for age, performance status, and stage, however, attenuated the relation to Type 1, leaving only Type 5 as a significantly related personality factor.Conclusion : A high Type 5 tendency may predict poor survival in lung cancer patients, whereas Types 1 and 4 may not be independent predictors.