MRI-ASL perfusion imaging -evaluation in pediatric brain and moyamoya disease-

1.MRI-ASL （FAIR）灌注成像中的脑血流SPIO脑灌注成像：SPIO与GdOur的个体内对照随机交叉比较研究结果显示，SPIO和gd的灌注成像在临床上是等效的。MRI-ASL （FAIR）灌注成像：FAIR与Gd灌注的个体内对照随机交叉比较研究我们的结果表明，FAIR和Gd灌注时皮层和白质的对比良好。3 . FAIR与Gd灌注相对血流量或血容量呈良好的正相关关系（r分别为0.78和0.448）。4 . MRI-ASL （FAIR）灌注成像发育中的脑血流区域模式与以往文献报道的PET数据相似，但FAIR图像的低信噪比暂停了一个问题。儿童烟雾病的后循环和缺血性卒中我们的研究结果表明，受影响的大脑后动脉的轻脑膜侧支减少与完全性卒中密切相关，而不是短暂性缺血发作，硬膜外侧支可能不足以补偿轻脑膜侧支的减少。早期累及大脑半球的大脑后动脉和较不严重的颈内动脉病变可能是幼儿中风发生率高的原因。

1.Cerebral blood flow in MRI-ASL (FAIR) perfusion imaging2.SPIO Brain Perfusion Imaging : Intraindividually Controlled Randomized Crossover Comparison Study of SPIO versus GdOur results showed a clinical equivalence of perfusion imaging using SPIO and Gd.3.MRI-ASL (FAIR) perfusion imaging : Intraindividually Controlled Randomized Crossover Comparison Study of FAIR versus Gd perfusionOur results indicate that good contrast between the cortex and white matter in both FAIR and Gd perfusion. Good positive relation ship was seen between in FAIR and in the relative blood flow or blood volume in Gd perfusion (r = 0.78 and 0.448, respectively).4.MRI-ASL (FAIR) perfusion imaging in the developing brainRegional pattern of the cerebral bloofd flow derived from FAIR was similar to the PET data reported in the previous literatures, however low signal to noise ratio in FAIR image paused a problem.5.Posterior Circulation and Ischemic Stroke in Pediatric Moyamoya DiseaseOur results indicate that reduced leptomeningeal collaterals from affected posterior cerebral artery are closely related to completed strokes rather than transient ischmic attask and transdural collaterals may not be sufficient to compensate for reduced leptomeningeal collaterals. The early involvement of posterior cerebral artery in hemispheres with the less advanced internal carotid artery lesions might be resposnsible for the high prevalence of completed strokes in young children.