Differentiation of finger plethysmographical vector index to the vascular tone and blood pressure related components : a simple new measure of the cardiovascular reactivity type

1.定义了一个新的向量指数（VI），并将VI与血管张力和血压相关成分区分开来。在各种心理应激条件下，VI与血压高度相关，且VI的方向性稳定。考虑到用于估计VI及其方向的复杂计算，可以简单地使用归一化的脉搏体积（NPV ; Sawada等人，2001）将上级于VI。2.我们提出了一种新的测量手指动脉弹性的方法。根据手指动脉压力（P）-容积（V）关系的指数模型（V=a-b×exp（exp）），将参数n定义为手指动脉弹性指数（FEI）。我们开发了一种新的FEI估计方法，它不受依从性的影响，因此不受血压测量的影响。应用我们提出的贵族评价方法申请专利。3.肱动脉血流介导的舒张功能（%FMD）超声显像是一种对人体内皮功能的验证性检测。Kuvin等人（2003）通过手指光电容积描记图（PWA）开发了外周动脉内皮试验。我们改进了PWA应用NPV的手指动脉的流量介导的扩张，并主张手指动脉流量介导的扩张率（FFMDR）作为一个简单的措施内皮功能。FFMDR和%FMD之间的相关性似乎相当高（r=0.67，n=35，年轻健康男性受试者）。

1.We defined a new vector index (VI) derived from finger photoplethysmogram and differentiated VI to the vascular tone and blood pressure related components. Under various mental stress conditions, VI revealed to be highly correlated with blood pressure and the orientation of VI seemed to be stable. Considering the complex calculation for estimating VI and its orientation, simple use of the normalized pulse volume (NPV ; Sawada et al., 2001) will be superior to VI.2.We advocated a new measure of the finger arterial elasticity derived from finger photoplethysmogram. Based on our exponential model of the pressure (P)-volume (V) relationship in the finger artery (V=a-b×exp(nP)), the parameter n is defined as finger arterial elasticity index (FEI). We developed a new estimating method for FEI, which were free from compliance and thus from blood pressure measurement. We applied to get patent by our noble estimation method.3.Ultrasonic imaging of the flow mediated-dilation (%FMD) in brachial artery is a confirmatory testing of human endotherial function. Kuvin et al. (2003) developed a peripheral arterial endotherial testing by finger photoplethysmogram (PWA). We improved PWA by applying NPV for flow mediated dilation of the finger artery and advocated finger arterial flow-mediated dilation ratio (FFMDR) as a simple measure of the endotherial function. Correlation between FFMDR and %FMD seemed to be reasonably high (r=0.67, n=35, young healthy male subjects).