Fund a mental research for treatment of keloid and hypertrophic scar

我们先前已经证明，瘢痕疙瘩中的三磷酸腺苷(ATP)含量在很长一段时间内保持在较高水平。在瘢痕疙瘩中，无氧糖酵解可能与三磷酸腺苷的产生有关。在本研究中，我们对瘢痕疙瘩、增生性和萎缩性瘢痕中的血管进行了一定范围的计数，并测量了其内腔横截面积和乳酸浓度。瘢痕疙瘩中限定区域的平均数量最小，血管的平均内部面积也是最小的。血管的减少和狭窄可能会降低氧气的灌注量。瘢痕疙瘩的血液供应不足，而且这种情况持续存在。

We have previously shown that the adenosine triphosphate (ATP) content of keloids remains high for a long time. In keloids, anaerobic glycolysis may be related to the production of ATP. In this study, we counted the vessels in keloids, hypertrophic and atrophic scars in a defined area, and measured the cross-sectional areas of their internal lumens immunohistopathologically and the lactate concentrations. The mean number in a defined area was smallest in keloids as was the mean internal area of vessels. The decreased and narrowed vessels may reduce oxygen perfusion. The blood supply to keloids is inadequate, and this persists.