Functional specificity of two closely related bHLH transcription factors during stomatal development in grasses (B11*)

两个密切相关的转录因子决定了草类气孔的两个形态特征：BdMUTE招募SCs并指导GC前体分裂，而BdFAMA协调GC分化和形态发生。然而，BdMUTE如何在GC和SC谱系中执行不同的功能，以及GC谱系中BdMUTE和BdFAMA具体控制哪些发育程序，仍是完全未知的。我们将通过应用显微镜、气体交换生理学、转录组学和发育心理遗传学来破译BdMUTE和BdFAMA在模式草Brachypodium disachyon发育GCs中的功能特异性。

Two closely related transcription factors determine the two morphological hallmarks of grass stomata; BdMUTE recruits SCs and guides GC precursor division, while BdFAMA orchestrates GC differen-tiation and morphogenesis. Yet, how BdMUTE executes distinct functions in the GC and SC lineage and which developmental programs are specifically controlled by BdMUTE and BdFAMA in the GC lineage is completely unknown. We will decode the functional specificity of BdMUTE and BdFAMA in developing GCs by applying microscopy, gas-exchange physiology, transcriptomics and develop-mental genetics in the model grass Brachypodium distachyon.